Detalhe da pesquisa
1.
Convergence of multiple RNA-silencing pathways on GW182/TNRC6.
Mol Cell
; 83(14): 2478-2492.e8, 2023 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37369201
2.
A common mechanism of Sec61 translocon inhibition by small molecules.
Nat Chem Biol
; 19(9): 1063-1071, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37169959
3.
A reversible haploid mouse embryonic stem cell biobank resource for functional genomics.
Nature
; 550(7674): 114-118, 2017 10 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28953874
4.
Discovery of a ZIP7 inhibitor from a Notch pathway screen.
Nat Chem Biol
; 15(2): 179-188, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30643281
5.
TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks.
Mol Cell
; 51(6): 829-39, 2013 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-24035500
6.
Deliberations on Natural Products and Future Directions in the Pharmaceutical Industry.
Chimia (Aarau)
; 75(7): 620-633, 2021 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34523403
7.
CRISPR-UMI: single-cell lineage tracing of pooled CRISPR-Cas9 screens.
Nat Methods
; 14(12): 1191-1197, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-29039415
8.
Kendomycin Cytotoxicity against Bacterial, Fungal, and Mammalian Cells Is Due to Cation Chelation.
J Nat Prod
; 83(4): 965-971, 2020 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32182062
9.
Cladosporin Derivatives Obtained by Biotransformation Provide Guidance for the Focused Derivatization of this Antimalarial Lead Compound.
Chembiochem
; 20(5): 650-654, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30347507
10.
Design and Synthesis of Metabolically Stable tRNA Synthetase Inhibitors Derived from Cladosporin.
Chembiochem
; 20(5): 644-649, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30462880
11.
Stendomycin selectively inhibits TIM23-dependent mitochondrial protein import.
Nat Chem Biol
; 13(12): 1239-1244, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28991239
12.
High-Resolution Genetics Identifies the Lipid Transfer Protein Sec14p as Target for Antifungal Ergolines.
PLoS Genet
; 12(11): e1006374, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27855158
13.
PrP-containing aggresomes are cytosolic components of an ER quality control mechanism.
J Cell Sci
; 129(19): 3635-3647, 2016 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27550517
14.
Decatransin, a new natural product inhibiting protein translocation at the Sec61/SecYEG translocon.
J Cell Sci
; 128(6): 1217-29, 2015 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25616894
15.
Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease.
PLoS Pathog
; 11(7): e1005058, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26186534
16.
Dark chemical matter as a promising starting point for drug lead discovery.
Nat Chem Biol
; 11(12): 958-66, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26479441
17.
Gift from Nature: Cyclomarinâ A Kills Mycobacteria and Malaria Parasites by Distinct Modes of Action.
Chembiochem
; 16(17): 2433-6, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26472355
18.
Nannocystinâ A: an Elongation Factor 1 Inhibitor from Myxobacteria with Differential Anti-Cancer Properties.
Angew Chem Int Ed Engl
; 54(35): 10149-54, 2015 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26179970
19.
Organization of organelles within hyphae of Ashbya gossypii revealed by electron tomography.
Eukaryot Cell
; 12(11): 1423-32, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23771903
20.
The transcription factor ZNF469 regulates collagen production in liver fibrosis.
bioRxiv
; 2024 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38712281