Detalhe da pesquisa
1.
Necrosis Links Neurodegeneration and Neuroinflammation in Neurodegenerative Disease.
Int J Mol Sci
; 25(7)2024 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38612448
2.
The intellectual disability gene PQBP1 rescues Alzheimer's disease pathology.
Mol Psychiatry
; 23(10): 2090-2110, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30283027
3.
RpA1 ameliorates symptoms of mutant ataxin-1 knock-in mice and enhances DNA damage repair.
Hum Mol Genet
; 25(20): 4432-4447, 2016 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28173122
4.
Targeting TEAD/YAP-transcription-dependent necrosis, TRIAD, ameliorates Huntington's disease pathology.
Hum Mol Genet
; 25(21): 4749-4770, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28171658
5.
Comprehensive phosphoproteome analysis unravels the core signaling network that initiates the earliest synapse pathology in preclinical Alzheimer's disease brain.
Hum Mol Genet
; 24(2): 540-58, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25231903
6.
Dynamic molecular network analysis of iPSC-Purkinje cells differentiation delineates roles of ISG15 in SCA1 at the earliest stage.
Commun Biol
; 7(1): 413, 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38594382
7.
Mutant α-synuclein propagates via the lymphatic system of the brain in the monomeric state.
Cell Rep
; 42(8): 112962, 2023 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37591248
8.
PQBP5/NOL10 maintains and anchors the nucleolus under physiological and osmotic stress conditions.
Nat Commun
; 14(1): 9, 2023 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36599853
9.
AAV-mediated editing of PMP22 rescues Charcot-Marie-Tooth disease type 1A features in patient-derived iPS Schwann cells.
Commun Med (Lond)
; 3(1): 170, 2023 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38017287
10.
Prediction and verification of the AD-FTLD common pathomechanism based on dynamic molecular network analysis.
Commun Biol
; 4(1): 961, 2021 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34385591
11.
Tau activates microglia via the PQBP1-cGAS-STING pathway to promote brain inflammation.
Nat Commun
; 12(1): 6565, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34782623
12.
Hepta-Histidine Inhibits Tau Aggregation.
ACS Chem Neurosci
; 12(16): 3015-3027, 2021 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34319089
13.
HMGB1 signaling phosphorylates Ku70 and impairs DNA damage repair in Alzheimer's disease pathology.
Commun Biol
; 4(1): 1175, 2021 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34635772
14.
DNA damage in embryonic neural stem cell determines FTLDs' fate via early-stage neuronal necrosis.
Life Sci Alliance
; 4(7)2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34130995
15.
YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology.
Nat Commun
; 11(1): 507, 2020 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31980612
16.
Ser46-Phosphorylated MARCKS Is a Marker of Neurite Degeneration at the Pre-aggregation Stage in PD/DLB Pathology.
eNeuro
; 5(4)2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30225354
17.
Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology.
Nat Commun
; 9(1): 433, 2018 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29382817
18.
Developmental YAPdeltaC determines adult pathology in a model of spinocerebellar ataxia type 1.
Nat Commun
; 8(1): 1864, 2017 11 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29192206
19.
HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer's disease.
Sci Rep
; 6: 31895, 2016 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27557632
20.
Identification of hepta-histidine as a candidate drug for Huntington's disease by in silico-in vitro- in vivo-integrated screens of chemical libraries.
Sci Rep
; 6: 33861, 2016 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27653664