Detalhe da pesquisa
1.
Microglia-synapse engulfment via PtdSer-TREM2 ameliorates neuronal hyperactivity in Alzheimer's disease models.
EMBO J
; 42(19): e113246, 2023 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37575021
2.
Complement C3-Deficient Mice Fail to Display Age-Related Hippocampal Decline.
J Neurosci
; 35(38): 13029-42, 2015 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26400934
3.
PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons.
Nat Neurosci
; 27(4): 643-655, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38424324
4.
New ELISAs with high specificity for soluble oligomers of amyloid ß-protein detect natural Aß oligomers in human brain but not CSF.
Alzheimers Dement
; 9(2): 99-112, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23375565
5.
Stimulation of TREM2 with agonistic antibodies-an emerging therapeutic option for Alzheimer's disease.
Lancet Neurol
; 22(11): 1048-1060, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37863592
6.
Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease.
Nat Neurosci
; 26(3): 406-415, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36747024
7.
Dynamic analysis of amyloid ß-protein in behaving mice reveals opposing changes in ISF versus parenchymal Aß during age-related plaque formation.
J Neurosci
; 31(44): 15861-9, 2011 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-22049429
8.
Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aß by microglia.
Glia
; 60(6): 993-1003, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22438044
9.
Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain.
Nat Neurosci
; 25(3): 306-316, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35260865
10.
Microglia states and nomenclature: A field at its crossroads.
Neuron
; 110(21): 3458-3483, 2022 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36327895
11.
Insight into the role of phosphatidylserine in complement-mediated synapse loss in Alzheimer's disease.
Fac Rev
; 10: 19, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33718936
12.
Understanding microglial diversity and implications for neuronal function in health and disease.
Dev Neurobiol
; 81(5): 507-523, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32757416
13.
Research priorities for neuroimmunology: identifying the key research questions to be addressed by 2030.
Wellcome Open Res
; 6: 194, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34778569
14.
The Jekyll and Hyde of TREM2.
Trends Neurosci
; 43(10): 739-740, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32863043
15.
Microglia modulate neurodegeneration in Alzheimer's and Parkinson's diseases.
Science
; 370(6512): 66-69, 2020 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33004513
16.
LRP promotes endocytosis and degradation, but not transcytosis, of the amyloid-beta peptide in a blood-brain barrier in vitro model.
Neurobiol Dis
; 30(1): 94-102, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18289866
17.
TREM2: Keeping Microglia Fit during Good Times and Bad.
Cell Metab
; 26(4): 590-591, 2017 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28978423
18.
Structured Illumination Microscopy for the Investigation of Synaptic Structure and Function.
Methods Mol Biol
; 1538: 155-167, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-27943190
19.
Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice.
Sci Transl Med
; 9(392)2017 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28566429
20.
Microglia: Phagocytosing to Clear, Sculpt, and Eliminate.
Dev Cell
; 38(2): 126-8, 2016 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27459063