Detalhe da pesquisa
1.
Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription.
Cell
; 178(5): 1159-1175.e17, 2019 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31442405
2.
Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease.
Mol Psychiatry
; 26(10): 5797-5811, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34112972
3.
A three-dimensional human neural cell culture model of Alzheimer's disease.
Nature
; 515(7526): 274-8, 2014 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25307057
4.
Silencing of the Drosophila ortholog of SOX5 leads to abnormal neuronal development and behavioral impairment.
Hum Mol Genet
; 26(8): 1472-1482, 2017 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28186563
5.
No association between CALHM1 and Alzheimer's disease risk.
Cell
; 135(6): 993-4; author reply 994-6, 2008 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-19070563
6.
Alzheimer's disease-associated TREM2 variants exhibit either decreased or increased ligand-dependent activation.
Alzheimers Dement
; 13(4): 381-387, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-27520774
7.
PLD3 gene variants and Alzheimer's disease.
Nature
; 520(7545): E7-8, 2015 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25832413
8.
Adjusting heterogeneous ascertainment bias for genetic association analysis with extended families.
BMC Med Genet
; 16: 62, 2015 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26286599
9.
Genetic associations with psychosis and affective disturbance in Alzheimer's disease.
Alzheimers Dement (N Y)
; 10(2): e12472, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38784964
10.
Novel CYP1B1-RMDN2 Alzheimer's disease locus identified by genome-wide association analysis of cerebral tau deposition on PET.
medRxiv
; 2023 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36993271
11.
Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity.
Hum Mol Genet
; 18(20): 3987-96, 2009 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19608551
12.
Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE.
Am J Hum Genet
; 83(5): 623-32, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18976728
13.
Assessment of Alzheimer's disease case-control associations using family-based methods.
Neurogenetics
; 10(1): 19-25, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18830724
14.
Gain-of-function mutations in protein kinase Cα (PKCα) may promote synaptic defects in Alzheimer's disease.
Sci Signal
; 9(427): ra47, 2016 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27165780
15.
The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk.
Neurology
; 83(15): 1353-8, 2014 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25186855
16.
Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta.
Neuron
; 78(4): 631-43, 2013 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23623698
17.
A current view of Alzheimer's disease.
F1000 Biol Rep
; 1: 54, 2009 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20948630
18.
GAB2 as an Alzheimer disease susceptibility gene: follow-up of genomewide association results.
Arch Neurol
; 66(2): 250-4, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19204163