Detalhe da pesquisa
1.
Recombinant human soluble domain of CD39L3 and ticagrelor: cardioprotective effects in experimental myocardial infarction.
Eur Heart J
; 45(17): 1553-1567, 2024 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38486376
2.
Optimization of ketone-based P2Y(12) receptor antagonists as antithrombotic agents: pharmacodynamics and receptor kinetics considerations.
Bioorg Med Chem Lett
; 24(13): 2963-8, 2014 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24835983
3.
A modeling approach for compounds affecting body composition.
J Pharmacokinet Pharmacodyn
; 40(6): 651-67, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24158456
4.
Discovery of AZD4831, a Mechanism-Based Irreversible Inhibitor of Myeloperoxidase, As a Potential Treatment for Heart Failure with Preserved Ejection Fraction.
J Med Chem
; 65(17): 11485-11496, 2022 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36005476
5.
Subcutaneous delivery of FGF21 mRNA therapy reverses obesity, insulin resistance, and hepatic steatosis in diet-induced obese mice.
Mol Ther Nucleic Acids
; 28: 500-513, 2022 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35592498
6.
Migratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors.
Nat Cell Biol
; 24(5): 659-671, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35550611
7.
Functionalized lipid nanoparticles for subcutaneous administration of mRNA to achieve systemic exposures of a therapeutic protein.
Mol Ther Nucleic Acids
; 24: 369-384, 2021 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33868782
8.
Structural analysis identifies an escape route from the adverse lipogenic effects of liver X receptor ligands.
Commun Biol
; 2: 431, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31799433
9.
Overexpressing cell systems are a competitive option to primary adipocytes when predicting in vivo potency of dual GPR81/GPR109A agonists.
Eur J Pharm Sci
; 114: 155-165, 2018 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29180298
10.
Correction to "Discovery of AZD4831, a Mechanism-Based Irreversible Inhibitor of Myeloperoxidase, As a Potential Treatment for Heart Failure with Preserved Ejection Fraction".
J Med Chem
; 65(19): 13482, 2022 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36190771
11.
Discovery of AZD6642, an inhibitor of 5-lipoxygenase activating protein (FLAP) for the treatment of inflammatory diseases.
J Med Chem
; 58(2): 897-911, 2015 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25478788
12.
Novel Zn2+ Modulated GPR39 Receptor Agonists Do Not Drive Acute Insulin Secretion in Rodents.
PLoS One
; 10(12): e0145849, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26720709