Detalhe da pesquisa
1.
Functional and structural insights into activation of TRPV2 by weak acids.
EMBO J
; 43(11): 2264-2290, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38671253
2.
Shared structural mechanisms of general anaesthetics and benzodiazepines.
Nature
; 585(7824): 303-308, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32879488
3.
tRNA shape is an identity element for an archaeal pyrrolysyl-tRNA synthetase from the human gut.
Nucleic Acids Res
; 52(2): 513-524, 2024 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38100361
4.
Biophysical characterization of calcium-binding and modulatory-domain dynamics in a pentameric ligand-gated ion channel.
Proc Natl Acad Sci U S A
; 119(50): e2210669119, 2022 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36480474
5.
Differential interactions of resting, activated, and desensitized states of the α7 nicotinic acetylcholine receptor with lipidic modulators.
Proc Natl Acad Sci U S A
; 119(43): e2208081119, 2022 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36251999
6.
Probing solution structure of the pentameric ligand-gated ion channel GLIC by small-angle neutron scattering.
Proc Natl Acad Sci U S A
; 118(37)2021 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34504004
7.
Structural basis for allosteric transitions of a multidomain pentameric ligand-gated ion channel.
Proc Natl Acad Sci U S A
; 117(24): 13437-13446, 2020 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32482881
8.
An open state of a voltage-gated sodium channel involving a π-helix and conserved pore-facing asparagine.
Biophys J
; 121(1): 11-22, 2022 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34890580
9.
Regulation of a pentameric ligand-gated ion channel by a semiconserved cationic lipid-binding site.
J Biol Chem
; 297(2): 100899, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34157288
10.
A missense mutation converts the Na+,K+-ATPase into an ion channel and causes therapy-resistant epilepsy.
J Biol Chem
; 297(6): 101355, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34717959
11.
Allosteric potentiation of a ligand-gated ion channel is mediated by access to a deep membrane-facing cavity.
Proc Natl Acad Sci U S A
; 115(42): 10672-10677, 2018 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30275330
12.
Molecular Dynamics Simulations of Ion Channels.
Trends Biochem Sci
; 46(7): 621-622, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33941431
13.
Sharing Data from Molecular Simulations.
J Chem Inf Model
; 59(10): 4093-4099, 2019 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31525920
14.
Permeating disciplines: Overcoming barriers between molecular simulations and classical structure-function approaches in biological ion transport.
Biochim Biophys Acta Biomembr
; 1860(4): 927-942, 2018 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29258839
15.
Seeking structural specificity: direct modulation of pentameric ligand-gated ion channels by alcohols and general anesthetics.
Pharmacol Rev
; 66(2): 396-412, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24515646
16.
Functional characterization of neurotransmitter activation and modulation in a nematode model ligand-gated ion channel.
J Neurochem
; 138(2): 243-53, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27102368
17.
Ethanol Modulation is Quantitatively Determined by the Transmembrane Domain of Human α1 Glycine Receptors.
Alcohol Clin Exp Res
; 39(6): 962-8, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25973519
18.
Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC).
J Biol Chem
; 288(12): 8355-8364, 2013 Mar 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23364792
19.
Structural basis for alcohol modulation of a pentameric ligand-gated ion channel.
Proc Natl Acad Sci U S A
; 108(29): 12149-54, 2011 Jul 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21730162
20.
Effects of disturbance associated with seismic exploration for oil and gas reserves in coastal marshes.
Environ Manage
; 54(1): 30-50, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24788940