Detalhe da pesquisa
1.
Targeting cathepsin S promotes activation of OLF1-BDNF/TrkB axis to enhance cognitive function.
J Biomed Sci
; 31(1): 46, 2024 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38725007
2.
Novel FLT3/AURK multikinase inhibitor is efficacious against sorafenib-refractory and sorafenib-resistant hepatocellular carcinoma.
J Biomed Sci
; 29(1): 5, 2022 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35062934
3.
A critical overview of current progress for COVID-19: development of vaccines, antiviral drugs, and therapeutic antibodies.
J Biomed Sci
; 29(1): 68, 2022 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36096815
4.
Natural product myricetin is a pan-KDM4 inhibitor which with poly lactic-co-glycolic acid formulation effectively targets castration-resistant prostate cancer.
J Biomed Sci
; 29(1): 29, 2022 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35534851
5.
Identification of Entry Inhibitors against Delta and Omicron Variants of SARS-CoV-2.
Int J Mol Sci
; 23(7)2022 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35409412
6.
One-Pot Synthesis of Dibenzo[b,f]oxepines and Total Synthesis of Bauhinoxepin C.
J Org Chem
; 86(2): 1955-1963, 2021 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33400878
7.
Briarenols W-Z: Chlorine-Containing Polyoxygenated Briaranes from Octocoral Briareum stechei (Kükenthal, 1908).
Mar Drugs
; 19(2)2021 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-33572535
8.
Drug-like property optimization: Discovery of orally bioavailable quinazoline-based multi-targeted kinase inhibitors.
Bioorg Chem
; 98: 103689, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32171993
9.
Biomimetic Syntheses of (±)-Isopalhinineâ A, (±)-Palhinineâ A, and (±)-Palhinineâ D.
Angew Chem Int Ed Engl
; 57(47): 15572-15576, 2018 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30284752
10.
Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules.
Proc Natl Acad Sci U S A
; 110(19): E1779-87, 2013 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23610398
11.
Identification of ligand efficient, fragment-like hits from an HTS library: structure-based virtual screening and docking investigations of 2H- and 3H-pyrazolo tautomers for Aurora kinase A selectivity.
J Comput Aided Mol Des
; 29(1): 89-100, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25344840
12.
CDKN1A-mediated responsiveness of MLL-AF4-positive acute lymphoblastic leukemia to Aurora kinase-A inhibitors.
Int J Cancer
; 135(3): 751-62, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24382688
13.
Influence of Ring Strain on the Formation of Rearrangement vs Cyclization Isotwistane Products in the Acyl Radical Reaction of Bicyclo[2.2.2]octanone.
Org Lett
; 25(43): 7757-7762, 2023 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37738398
14.
A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effects.
Eur J Med Chem
; 258: 115608, 2023 Oct 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37437352
15.
Development of Furanopyrimidine-Based Orally Active Third-Generation EGFR Inhibitors for the Treatment of Non-Small Cell Lung Cancer.
J Med Chem
; 66(4): 2566-2588, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36749735
16.
Identification of BPR3P0128 as an inhibitor of cap-snatching activities of influenza virus.
Antimicrob Agents Chemother
; 56(2): 647-57, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21930871
17.
Inhibition of HIV-1 Tat-mediated transcription by a coumarin derivative, BPRHIV001, through the Akt pathway.
J Virol
; 85(17): 9114-26, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21697490
18.
Mimicking H3 Substrate Arginine in the Design of G9a Lysine Methyltransferase Inhibitors for Cancer Therapy: A Computational Study for Structure-Based Drug Design.
ACS Omega
; 6(9): 6100-6111, 2021 Mar 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33718701
19.
Colloidal Assemblies Composed of Polymeric Micellar/Emulsified Systems Integrate Cancer Therapy Combining a Tumor-Associated Antigen Vaccine and Chemotherapeutic Regimens.
Nanomaterials (Basel)
; 11(7)2021 Jul 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34361230
20.
Overcoming vincristine resistance in cancer: Computational design and discovery of piperine-inspired P-glycoprotein inhibitors.
Chem Biol Drug Des
; 97(1): 51-66, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32633857