RESUMO
Humans are motivated to give norm violators their just deserts through costly punishment even as unaffected third parties (i.e., third-party punishment, TPP). A great deal of individual variability exists in costly punishment; however, how this variability particularly in TPP is represented by the brain's intrinsic network architecture remains elusive. Here, we examined whether inter-individual differences in the propensity for TPP can be predicted based on resting-state functional connectivity (RSFC) combining an economic TPP game with task-free functional neuroimaging and a multivariate prediction framework. Our behavioral results revealed that TPP punishment increased with the severity of unfairness for offers. People with higher TPP propensity punished more harshly across norm-violating scenarios. Our neuroimaging findings showed RSFC within the frontoparietal network predicted individual differences in TPP propensity. Our findings contribute to understanding the neural fingerprint for an individual's propensity to costly punish strangers, and shed some light on how social norm enforcement behaviors are represented by the brain's intrinsic network architecture.
Assuntos
Individualidade , Punição , Humanos , NeuroimagemRESUMO
Iterative reconstruction has demonstrated superior performance in medical imaging under compressed, sparse, and limited-view sensing scenarios. However, iterative reconstruction algorithms are slow to converge and rely heavily on hand-crafted parameters to achieve good performance. Many iterations are usually required to reconstruct a high-quality image, which is computationally expensive due to repeated evaluations of the physical model. While learned iterative reconstruction approaches such as model-based learning (MBLr) can reduce the number of iterations through convolutional neural networks, it still requires repeated evaluations of the physical models at each iteration. Therefore, the goal of this study is to develop a Fast Iterative Reconstruction (FIRe) algorithm that incorporates a learned physical model into the learned iterative reconstruction scheme to further reduce the reconstruction time while maintaining robust reconstruction performance. We also propose an efficient training scheme for FIRe, which releases the enormous memory footprint required by learned iterative reconstruction methods through the concept of recursive training. The results of our proposed method demonstrate comparable reconstruction performance to learned iterative reconstruction methods with a 9x reduction in computation time and a 620x reduction in computation time compared to variational reconstruction.
RESUMO
Levator ani muscle (LAM) avulsion is a common complication of vaginal childbirth and is linked to several pelvic floor disorders. Diagnosing and treating these conditions require imaging of the pelvic floor and examination of the obtained images, which is a time-consuming process subjected to operator variability. In our study, we proposed using deep learning (DL) to automate the segmentation of the LAM from 3D endovaginal ultrasound images (EVUS) to improve diagnostic accuracy and efficiency. Over one thousand images extracted from the 3D EVUS data of healthy subjects and patients with pelvic floor disorders were utilized for the automated LAM segmentation. A U-Net model was implemented, with Intersection over Union (IoU) and Dice metrics being used for model performance evaluation. The model achieved a mean Dice score of 0.86, demonstrating a better performance than existing works. The mean IoU was 0.76, indicative of a high degree of overlap between the automated and manual segmentation of the LAM. Three other models including Attention UNet, FD-UNet and Dense-UNet were also applied on the same images which showed comparable results. Our study demonstrated the feasibility and accuracy of using DL segmentation with U-Net architecture to automate LAM segmentation to reduce the time and resources required for manual segmentation of 3D EVUS images. The proposed method could become an important component in AI-based diagnostic tools, particularly in low socioeconomic regions where access to healthcare resources is limited. By improving the management of pelvic floor disorders, our approach may contribute to better patient outcomes in these underserved areas.
RESUMO
Conventional reconstruction methods for photoacoustic images are not suitable for the scenario of sparse sensing and geometrical limitation. To overcome these challenges and enhance the quality of reconstruction, several learning-based methods have recently been introduced for photoacoustic tomography reconstruction. The goal of this study is to compare and systematically evaluate the recently proposed learning-based methods and modified networks for photoacoustic image reconstruction. Specifically, learning-based post-processing methods and model-based learned iterative reconstruction methods are investigated. In addition to comparing the differences inherently brought by the models, we also study the impact of different inputs on the reconstruction effect. Our results demonstrate that the reconstruction performance mainly stems from the effective amount of information carried by the input. The inherent difference of the models based on the learning-based post-processing method does not provide a significant difference in photoacoustic image reconstruction. Furthermore, the results indicate that the model-based learned iterative reconstruction method outperforms all other learning-based post-processing methods in terms of generalizability and robustness.