Detalhe da pesquisa
1.
Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils.
Proc Natl Acad Sci U S A
; 120(7): e2217835120, 2023 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36757890
2.
De novo designed protein inhibitors of amyloid aggregation and seeding.
Proc Natl Acad Sci U S A
; 119(34): e2206240119, 2022 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35969734
3.
Extended ß-Strands Contribute to Reversible Amyloid Formation.
ACS Nano
; 16(2): 2154-2163, 2022 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35132852
4.
Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies.
Nat Struct Mol Biol
; 29(6): 529-536, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35637421
5.
Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro.
Nat Commun
; 13(1): 5451, 2022 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36114178