Nontrivial superconductivity in topological MoTe2-x S x crystals.

Topological Weyl semimetals (TWSs) with pairs of Weyl points and topologically protected Fermi arc states have broadened the classification of topological phases and provide superior platform for study of topological superconductivity. Here we report the nontrivial superconductivity and topological features of sulfur-doped Td -phase MoTe2 with enhanced Tc compared with type-II TWS MoTe2 It is found that Td -phase S-doped MoTe2 (MoTe2-x S x , x ∼ 0.2) is a two-band s-wave bulk superconductor (∼0.13 meV and 0.26 meV), where the superconducting behavior can be explained by the s+- pairing model. Further, measurements of the quasi-particle interference (QPI) patterns and a comparison with band-structure calculations reveal the existence of Fermi arcs in MoTe2-x S x More interestingly, a relatively large superconducting gap (∼1.7 meV) is detected by scanning tunneling spectroscopy on the sample surface, showing a hint of topological nontrivial superconductivity based on the pairing of Fermi arc surface states. Our work demonstrates that the Td -phase MoTe2-x S x is not only a promising topological superconductor candidate but also a unique material for study of s+- superconductivity.

Switching energy dissipation pathway: in situ proton-induced transformation of AIE-active self-assemblies to boost photodynamic therapy.

With the morphological transformation of fluorescent self-assembled nanostructures, their functions can be varied simultaneously. However, little attention has been paid to the function variation in this process. Herein, we present aggregation-induced emission (AIE)-active self-assembled nanospheres to investigate the transformation-induced function variation by switching the energy dissipation pathway. The self-assembled nanospheres showed strong emission under neutral conditions, indicating that radiative decay dominates the energy dissipation. Under acidic conditions, the spheres transformed to vesicles and nanotubes, in which the excited energy was largely consumed by the intersystem crossing pathway and highly efficient reactive oxygen species (ROS) generation was afforded. In particular, this morphological transformation and function variation can smoothly proceed in acidic lysosomes, thus drastically boosting photodynamic cancer therapy.

A Facile Strategy of Boosting Photothermal Conversion Efficiency through State Transformation for Cancer Therapy.

Improving photothermal conversion efficiency (PCE) is critical to facilitate therapeutic performance during photothermal therapy (PTT). However, current strategies of prompting PCE always involve complex synthesis or modification of photothermal agents, thereby significantly inhibiting the practical applications and fundamental understanding of photothermal conversion. A facile strategy is herein present for boosting PCE by transforming photothermal agents from aggregated state to dispersed state. Compared to aggregated state, the developed photothermal agents with semiconducting nature can rotate freely in dispersed state, which allows for an efficient nonradiative dissipation through twisted intramolecular charge transfer (TICT) effect, consequentially offering excellent photothermal performance. Noteworthy, the state transformation can be achieved by virtue of releasing photothermal molecules from nanoparticles on the basis of a pH-responsive polymer nanocarrier, and the PCE is elevated from 43% to 60% upon changing the pH values from 7.4 to 5.0. Moreover, the nanoparticle disassembly and state transformation behaviors can also smoothly proceed in lysosome of cancer cells, demonstrating a distinct photothermal therapeutic performance for cancer ablation. It is hoped that this strategy of transforming state to boost PCE would be a new platform for practical applications of PTT technique.