Saccade eye movement in children with attention deficit hyperactivity disorder.

Objects: This study aims to investigate the saccade/anti-saccade eye movement in children with attention deficit/hyperactivity disorder (ADHD).Methods: Twelve children (8.8 ± 0.8 years) diagnosed with ADHD (DSM-V) and 12 control (9.1 ± 0.3 years) were invited to participate in the experiment where the iView Hi-SPEED eyetracker, with the sample rate at 500 Hz Binocular, was employed. The visual guided saccade (VGS) task was used to collect saccade latency and accuracy values. The anti-saccade task was used to collect saccade latency and accuracy values as well as the percentage of direction errors (PDE).Results: Children with ADHD showed a significant difference in latency in the 7.5° target and imprecision in both targets (7.5° and 15°) during the VGS task. Moreover, the ADHD group exhibited shorter latency (15° target) and significantly higher numbers in the Percentage of Direction Errors in the anti-saccade tasks than the control group.Conclusions: The results suggest that children with ADHD have the following difficulties: precise oculomotor control, oculomotor response inhibition function and basic visual attention.

A neutral mononuclear rhenium(I) complex with a rare in situ-generated triazolyl ligand for the luminescence "turn-on" detection of histidine.

A rare in situ-generated mononuclear rhenium complex [Re(bpt)(CO)3(NH3)] (1, bpt = 3,5-bis(2-pyridyl)-1,2,4-triazolate) can be used as a "turn-on" luminescent probe for selectively sensing L-histidine against other amino acids. Compound 1 was prepared by reacting Re2(CO)10, 2-cyanopyridine and hydrazine with an in situ formed bpt ligand through cyclization via C-N and N-N couplings with its single-side chelating mode arrayed with respect to the Re center. Compound 1 was highly stable and showed a green light MLCT emission in DMF solution at 507 nm upon excitation at 360 nm. Interestingly, the emission from 1 could be quenched by the addition of metal ions such as Ni2+ and Cu2+ but the emission efficiently recovered with the introduction of histidine. However, histidine could only be selectively detected when a combination of compound 1 and Ni2+ was used. Therefore, the luminescence response of the Ni2+-modified compound 1 could be utilized as a "turn-on" probe for the selective detection of histidine. This work provides a simple method for developing new sensing platforms of a discrete metal complex based on rare in situ generation.