Detalhe da pesquisa
1.
METTL13 Methylation of eEF1A Increases Translational Output to Promote Tumorigenesis.
Cell
; 176(3): 491-504.e21, 2019 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30612740
2.
A hydride transfer complex reprograms NAD metabolism and bypasses senescence.
Mol Cell
; 81(18): 3848-3865.e19, 2021 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34547241
3.
mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1.
Mol Cell
; 67(6): 922-935.e5, 2017 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28918902
4.
Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth.
Nat Chem Biol
; 17(10): 1065-1074, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34168367
5.
nanoCAGE reveals 5' UTR features that define specific modes of translation of functionally related MTOR-sensitive mRNAs.
Genome Res
; 26(5): 636-48, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26984228
6.
Author Correction: Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth.
Nat Chem Biol
; 17(11): 1209, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34616097
7.
Author Correction: Selective inhibitors of mTORC1 activate 4EBP1 and suppress tumor growth.
Nat Chem Biol
; 17(8): 925, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-34188221
8.
RAS transformation requires CUX1-dependent repair of oxidative DNA damage.
PLoS Biol
; 12(3): e1001807, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24618719
9.
mTOR-sensitive translation: Cleared fog reveals more trees.
RNA Biol
; 14(10): 1299-1305, 2017 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28277937
10.
ZO-1 interacts with YB-1 in endothelial cells to regulate stress granule formation during angiogenesis.
Nat Commun
; 15(1): 4405, 2024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38782923
11.
O-GlcNAcylation of FOXK1 orchestrates the E2F pathway and promotes oncogenesis.
bioRxiv
; 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38463952
12.
The mitochondrial pyruvate carrier complex potentiates the efficacy of proteasome inhibitors in multiple myeloma.
Blood Adv
; 7(14): 3485-3500, 2023 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36920785
13.
CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax.
Cell Rep
; 42(9): 113084, 2023 09 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37716355
14.
EIF4A inhibition targets bioenergetic homeostasis in AML MOLM-14 cells in vitro and in vivo and synergizes with cytarabine and venetoclax.
J Exp Clin Cancer Res
; 41(1): 340, 2022 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36482393
15.
Mitochondrial complex IV defects induce metabolic and signaling perturbations that expose potential vulnerabilities in HCT116 cells.
FEBS Open Bio
; 12(5): 959-982, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35302710
16.
Perturbations of cancer cell metabolism by the antidiabetic drug canagliflozin.
Neoplasia
; 23(4): 391-399, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33784591
17.
Starvation-induced proteasome assemblies in the nucleus link amino acid supply to apoptosis.
Nat Commun
; 12(1): 6984, 2021 11 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34848715
18.
PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis.
Nat Commun
; 11(1): 3520, 2020 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32665551
19.
Oncogenic kinases and perturbations in protein synthesis machinery and energetics in neoplasia.
J Mol Endocrinol
; 62(2): R83-R103, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30072418
20.
mTOR as a central regulator of lifespan and aging.
F1000Res
; 82019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31316753