Detalhe da pesquisa
1.
Development of an Optical Nanosensor Incorporating a pH-Sensitive Quencher Dye for Potassium Imaging.
Anal Chem
; 87(21): 10684-7, 2015 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26444247
2.
Discovery of biaryl carboxylamides as potent RORγ inverse agonists.
Bioorg Med Chem Lett
; 25(15): 2991-7, 2015 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26048806
3.
Discovery of novel hepatoselective HMG-CoA reductase inhibitors for treating hypercholesterolemia: a bench-to-bedside case study on tissue selective drug distribution.
Bioorg Med Chem Lett
; 21(9): 2725-31, 2011 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21183342
4.
Substituted pyrazoles as hepatoselective HMG-CoA reductase inhibitors: discovery of (3R,5R)-7-[2-(4-fluoro-phenyl)-4-isopropyl-5-(4-methyl-benzylcarbamoyl)-2H-pyrazol-3-yl]-3,5-dihydroxyheptanoic acid (PF-3052334) as a candidate for the treatment of hypercholesterolemia.
J Med Chem
; 51(1): 31-45, 2008 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-18072721
5.
Antiproliferative Hybrid Analogs of the Hormone 1alpha,25-Dihydroxyvitamin D(3): Design, Synthesis, and Preliminary Biological Evaluation.
J Org Chem
; 62(10): 3299-3314, 1997 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-11671717
6.
Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase.
J Med Chem
; 51(13): 3804-13, 2008 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-18540668
7.
Arylpiperazine substituted heterocycles as selective alpha(1a) adrenergic antagonists.
Bioorg Med Chem Lett
; 12(17): 2443-6, 2002 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-12161153