RESUMO
This observation reports that a hepatitis B virus (HBV) reactivation, as the result of hepatitis C virus (HCV) eradication on a dominant HCV coinfected HBV/HCV patient, was subsequently prevented by treating both viral infections together. This finding raises the question as to whether preemptive HBV treatment should be prescribed along with HCV treatment to prevent HBV from being reactive after HCV eradication in coinfected HBV/HCV patients.
Assuntos
Adenina/análogos & derivados , Antivirais/uso terapêutico , Vírus da Hepatite B/fisiologia , Hepatite B/prevenção & controle , Hepatite C/tratamento farmacológico , Organofosfonatos/uso terapêutico , Ativação Viral/efeitos dos fármacos , Adenina/uso terapêutico , Adulto , Portador Sadio/tratamento farmacológico , Portador Sadio/virologia , Quimioterapia Combinada , Hepatite B/complicações , Hepatite B/tratamento farmacológico , Vírus da Hepatite B/efeitos dos fármacos , Hepatite C/complicações , Humanos , MasculinoRESUMO
Hepatitis E is transmitted mainly by water or food, but in industrialized countries, all routes of transmission have not been identified. We describe possible zoonotic transmission of hepatitis E virus that involved direct contact between a pet pig and its owner.
Assuntos
Vírus da Hepatite E/isolamento & purificação , Hepatite E/transmissão , Doenças dos Suínos/transmissão , Zoonoses , Adulto , Animais , Animais Domésticos , Anticorpos Antivirais/sangue , Reservatórios de Doenças/veterinária , Reservatórios de Doenças/virologia , Amplificação de Genes , Genótipo , Hepatite E/veterinária , Hepatite E/virologia , Vírus da Hepatite E/classificação , Vírus da Hepatite E/imunologia , Humanos , Fígado/enzimologia , Fases de Leitura Aberta , Filogenia , RNA Viral/química , RNA Viral/genética , Reação em Cadeia da Polimerase Via Transcriptase Reversa , Especificidade da Espécie , Suínos , Doenças dos Suínos/virologiaRESUMO
Liver involvement is usually a minor manifestation of Kawasaki disease and includes hepatobiliary dysfunction or gallbladder hydrops. We describe here an unusual case of jaundice revealing an adult onset Kawasaki disease. An 18-year-old man presented with abdominal pain and jaundice associated with cholestasis as the initial manifestation of Kawasaki disease. Abdominal evaluation (ultrasonography and CT-scan) did not find abnormality. Other signs typical of the Kawasaki disease occurred a few days later and permitted diagnosis. With aspirin and intravenous immunoglobulins, outcome was favorable without any cardiovascular complication. Our case suggests that Kawasaki disease should be added to the etiological list of painful febrile icterus in young patients.