Detalhe da pesquisa
1.
A G-quadruplex telomere targeting agent produces p16-associated senescence and chromosomal fusions in human prostate cancer cells.
Mol Cancer Ther
; 3(10): 1201-6, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15486186
2.
Trisubstituted acridine derivatives as potent and selective telomerase inhibitors.
J Med Chem
; 46(21): 4463-76, 2003 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-14521409
3.
Telomerase inhibitors in cancer therapy: current status and future directions.
Curr Opin Investig Drugs
; 4(6): 675-85, 2003 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12901225
4.
Acquired cellular resistance to flavopiridol in a human colon carcinoma cell line involves up-regulation of the telomerase catalytic subunit and telomere elongation. Sensitivity of resistant cells to combination treatment with a telomerase inhibitor.
Mol Pharmacol
; 64(5): 1101-8, 2003 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-14573759
5.
Evaluation of by disubstituted acridone derivatives as telomerase inhibitors: the importance of G-quadruplex binding.
Bioorg Med Chem Lett
; 14(23): 5845-9, 2004 Dec 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-15501053