Detalhe da pesquisa
1.
TIFAB regulates the TIFA-TRAF6 signaling pathway involved in innate immunity by forming a heterodimer complex with TIFA.
Proc Natl Acad Sci U S A
; 121(11): e2318794121, 2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38442163
2.
The membrane-linked adaptor FRS2ß fashions a cytokine-rich inflammatory microenvironment that promotes breast cancer carcinogenesis.
Proc Natl Acad Sci U S A
; 118(43)2021 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34663724
3.
Aberrant accumulation of NIK promotes tumor growth by dysregulating translation and post-translational modifications in breast cancer.
Cancer Cell Int
; 23(1): 57, 2023 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37005661
4.
A tetravalent peptide that binds to the RANK-binding region of TRAF6 via a multivalent interaction efficiently inhibits osteoclast differentiation.
Biochem Biophys Res Commun
; 636(Pt 1): 178-183, 2022 12 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36334442
5.
N-(4-Hydroxyphenyl) Retinamide Suppresses SARS-CoV-2 Spike Protein-Mediated Cell-Cell Fusion by a Dihydroceramide Δ4-Desaturase 1-Independent Mechanism.
J Virol
; 95(17): e0080721, 2021 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34106748
6.
A New 1,2-Naphthoquinone Derivative with Anti-lung Cancer Activity.
Chem Pharm Bull (Tokyo)
; 70(7): 477-482, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35786566
7.
TNF receptor-associated factor 6 (TRAF6) plays crucial roles in multiple biological systems through polyubiquitination-mediated NF-κB activation.
Proc Jpn Acad Ser B Phys Biol Sci
; 97(4): 145-160, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33840674
8.
Cell-cell and virus-cell fusion assay-based analyses of alanine insertion mutants in the distal α9 portion of the JRFL gp41 subunit from HIV-1.
J Biol Chem
; 294(14): 5677-5687, 2019 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30737278
9.
miR-146a-Traf6 regulatory axis controls autoimmunity and myelopoiesis, but is dispensable for hematopoietic stem cell homeostasis and tumor suppression.
Proc Natl Acad Sci U S A
; 114(34): E7140-E7149, 2017 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28784800
10.
HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains.
PLoS Pathog
; 13(1): e1006162, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28103322
11.
Molecular mechanisms of Streptococcus pneumoniae-targeted autophagy via pneumolysin, Golgi-resident Rab41, and Nedd4-1-mediated K63-linked ubiquitination.
Cell Microbiol
; 20(8): e12846, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29582580
12.
Critical roles of IκBα and RelA phosphorylation in transitional oscillation in NF-κB signaling module.
J Theor Biol
; 462: 479-489, 2019 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30496749
13.
Minimum structural requirements for inhibitors of the zinc finger protein TRAF6.
Bioorg Med Chem Lett
; 29(16): 2162-2167, 2019 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31272791
14.
Six-helix bundle completion in the distal C-terminal heptad repeat region of gp41 is required for efficient human immunodeficiency virus type 1 infection.
Retrovirology
; 15(1): 27, 2018 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29609648
15.
Dok-3 and Dok-1/-2 adaptors play distinctive roles in cell fusion and proliferation during osteoclastogenesis and cooperatively protect mice from osteopenia.
Biochem Biophys Res Commun
; 498(4): 967-974, 2018 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29548825
16.
The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response.
Nature
; 483(7391): 623-6, 2012 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22407319
17.
Integrative Network Analysis Combined with Quantitative Phosphoproteomics Reveals Transforming Growth Factor-beta Receptor type-2 (TGFBR2) as a Novel Regulator of Glioblastoma Stem Cell Properties.
Mol Cell Proteomics
; 15(3): 1017-31, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26670566
18.
Interaction of Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) and Vav3 in the Receptor Activator of Nuclear Factor κB (RANK) Signaling Complex Enhances Osteoclastogenesis.
J Biol Chem
; 291(39): 20643-60, 2016 09 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27507811
19.
Intratumoral bidirectional transitions between epithelial and mesenchymal cells in triple-negative breast cancer.
Cancer Sci
; 108(6): 1210-1222, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28371195
20.
Quantitative phosphoproteomics-based molecular network description for high-resolution kinase-substrate interactome analysis.
Bioinformatics
; 32(14): 2083-8, 2016 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27153602