Pesquisa | BVS IEC

1.

Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy.

Hong, Xin; Sullivan, Ryan J; Kalinich, Mark; Kwan, Tanya Todorova; Giobbie-Hurder, Anita; Pan, Shiwei; LiCausi, Joseph A; Milner, John D; Nieman, Linda T; Wittner, Ben S; Ho, Uyen; Chen, Tianqi; Kapur, Ravi; Lawrence, Donald P; Flaherty, Keith T; Sequist, Lecia V; Ramaswamy, Sridhar; Miyamoto, David T; Lawrence, Michael; Toner, Mehmet; Isselbacher, Kurt J; Maheswaran, Shyamala; Haber, Daniel A.

Proc Natl Acad Sci U S A ; 115(10): 2467-2472, 2018 03 06.

Artigo em Inglês | MEDLINE | ID: mdl-29453278

2.

Relevance of iPSC-derived human PGC-like cells at the surface of embryoid bodies to prechemotaxis migrating PGCs.

Mitsunaga, Shino; Odajima, Junko; Yawata, Shiomi; Shioda, Keiko; Owa, Chie; Isselbacher, Kurt J; Hanna, Jacob H; Shioda, Toshi.

Proc Natl Acad Sci U S A ; 114(46): E9913-E9922, 2017 11 14.

Artigo em Inglês | MEDLINE | ID: mdl-29087313

3.

An RNA-based signature enables high specificity detection of circulating tumor cells in hepatocellular carcinoma.

Kalinich, Mark; Bhan, Irun; Kwan, Tanya T; Miyamoto, David T; Javaid, Sarah; LiCausi, Joseph A; Milner, John D; Hong, Xin; Goyal, Lipika; Sil, Srinjoy; Choz, Melissa; Ho, Uyen; Kapur, Ravi; Muzikansky, Alona; Zhang, Huidan; Weitz, David A; Sequist, Lecia V; Ryan, David P; Chung, Raymond T; Zhu, Andrew X; Isselbacher, Kurt J; Ting, David T; Toner, Mehmet; Maheswaran, Shyamala; Haber, Daniel A.

Proc Natl Acad Sci U S A ; 114(5): 1123-1128, 2017 01 31.

Artigo em Inglês | MEDLINE | ID: mdl-28096363

4.

Erasure of DNA methylation, genomic imprints, and epimutations in a primordial germ-cell model derived from mouse pluripotent stem cells.

Miyoshi, Norikatsu; Stel, Jente M; Shioda, Keiko; Qu, Na; Odajima, Junko; Mitsunaga, Shino; Zhang, Xiangfan; Nagano, Makoto; Hochedlinger, Konrad; Isselbacher, Kurt J; Shioda, Toshi.

Proc Natl Acad Sci U S A ; 113(34): 9545-50, 2016 08 23.

Artigo em Inglês | MEDLINE | ID: mdl-27486249

5.

Expressomal approach for comprehensive analysis and visualization of ligand sensitivities of xenoestrogen responsive genes.

Shioda, Toshi; Rosenthal, Noël F; Coser, Kathryn R; Suto, Mizuki; Phatak, Mukta; Medvedovic, Mario; Carey, Vincent J; Isselbacher, Kurt J.

Proc Natl Acad Sci U S A ; 110(41): 16508-13, 2013 Oct 08.

Artigo em Inglês | MEDLINE | ID: mdl-24062438

6.

Isolation of circulating tumor cells using a microvortex-generating herringbone-chip.

Stott, Shannon L; Hsu, Chia-Hsien; Tsukrov, Dina I; Yu, Min; Miyamoto, David T; Waltman, Belinda A; Rothenberg, S Michael; Shah, Ajay M; Smas, Malgorzata E; Korir, George K; Floyd, Frederick P; Gilman, Anna J; Lord, Jenna B; Winokur, Daniel; Springer, Simeon; Irimia, Daniel; Nagrath, Sunitha; Sequist, Lecia V; Lee, Richard J; Isselbacher, Kurt J; Maheswaran, Shyamala; Haber, Daniel A; Toner, Mehmet.

Proc Natl Acad Sci U S A ; 107(43): 18392-7, 2010 Oct 26.

Artigo em Inglês | MEDLINE | ID: mdl-20930119

7.

Antiestrogen-resistant subclones of MCF-7 human breast cancer cells are derived from a common monoclonal drug-resistant progenitor.

Coser, Kathryn R; Wittner, Ben S; Rosenthal, Noël F; Collins, Sabrina C; Melas, Antonia; Smith, Shannon L; Mahoney, Crystal J; Shioda, Keiko; Isselbacher, Kurt J; Ramaswamy, Sridhar; Shioda, Toshi.

Proc Natl Acad Sci U S A ; 106(34): 14536-41, 2009 Aug 25.

Artigo em Inglês | MEDLINE | ID: mdl-19706540

8.

Production and Analysis of Human Primordial Germ Cell-Like Cells.

Mitsunaga, Shino; Shioda, Keiko; Hanna, Jacob H; Isselbacher, Kurt J; Shioda, Toshi.

Methods Mol Biol ; 2195: 125-145, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-32852762

9.

Transcriptomic and Epigenetic Preservation of Genetic Sex Identity in Estrogen-feminized Male Chicken Embryonic Gonads.

Shioda, Keiko; Odajima, Junko; Kobayashi, Misato; Kobayashi, Mutsumi; Cordazzo, Bianca; Isselbacher, Kurt J; Shioda, Toshi.

Endocrinology ; 162(1)2021 01 01.

Artigo em Inglês | MEDLINE | ID: mdl-33170207

10.

Generation of Human Primordial Germ Cell-like Cells at the Surface of Embryoid Bodies from Primed-pluripotency Induced Pluripotent Stem Cells.

Mitsunaga, Shino; Shioda, Keiko; Isselbacher, Kurt J; Hanna, Jacob H; Shioda, Toshi.

J Vis Exp ; (143)2019 01 11.

Artigo em Inglês | MEDLINE | ID: mdl-30688291

11.

Regulation of expression of BIK proapoptotic protein in human breast cancer cells: p53-dependent induction of BIK mRNA by fulvestrant and proteasomal degradation of BIK protein.

Hur, Jingyung; Bell, Daphne W; Dean, Kathleen L; Coser, Kathryn R; Hilario, Pablo C; Okimoto, Ross A; Tobey, Erica M; Smith, Shannon L; Isselbacher, Kurt J; Shioda, Toshi.

Cancer Res ; 66(20): 10153-61, 2006 Oct 15.

Artigo em Inglês | MEDLINE | ID: mdl-17047080

12.

Irritable bowel syndrome: the possible benefits of probiotics.

Isselbacher, Kurt J.

Postgrad Med ; 117(5): 7, 2005 May.

Artigo em Inglês | MEDLINE | ID: mdl-15948360

13.

Calprotectin: a predictive marker of a relapse in ulcerative colitis.

Isselbacher, Kurt J.

Postgrad Med ; 117(5): 8, 2005 May.

Artigo em Inglês | MEDLINE | ID: mdl-15948362

14.

Importance of dosage standardization for interpreting transcriptomal signature profiles: evidence from studies of xenoestrogens.

Shioda, Toshi; Chesnes, Jessica; Coser, Kathryn R; Zou, Lihua; Hur, Jingyung; Dean, Kathleen L; Sonnenschein, Carlos; Soto, Ana M; Isselbacher, Kurt J.

Proc Natl Acad Sci U S A ; 103(32): 12033-8, 2006 Aug 08.

Artigo em Inglês | MEDLINE | ID: mdl-16882715

15.

Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib.

Kwak, Eunice L; Sordella, Raffaella; Bell, Daphne W; Godin-Heymann, Nadia; Okimoto, Ross A; Brannigan, Brian W; Harris, Patricia L; Driscoll, David R; Fidias, Panos; Lynch, Thomas J; Rabindran, Sridhar K; McGinnis, John P; Wissner, Allan; Sharma, Sreenath V; Isselbacher, Kurt J; Settleman, Jeffrey; Haber, Daniel A.

Proc Natl Acad Sci U S A ; 102(21): 7665-70, 2005 May 24.

Artigo em Inglês | MEDLINE | ID: mdl-15897464

16.

Retrospective. Paul C. Zamecnik (1912-2009).

Isselbacher, Kurt J.

Science ; 326(5958): 1359, 2009 Dec 04.

Artigo em Inglês | MEDLINE | ID: mdl-19965748

17.

Global analysis of ligand sensitivity of estrogen inducible and suppressible genes in MCF7/BUS breast cancer cells by DNA microarray.

Coser, Kathryn R; Chesnes, Jessica; Hur, Jingyung; Ray, Sandip; Isselbacher, Kurt J; Shioda, Toshi.

Proc Natl Acad Sci U S A ; 100(24): 13994-9, 2003 Nov 25.

Artigo em Inglês | MEDLINE | ID: mdl-14610279

18.

The Bik BH3-only protein is induced in estrogen-starved and antiestrogen-exposed breast cancer cells and provokes apoptosis.

Hur, Jingyung; Chesnes, Jessica; Coser, Kathryn R; Lee, Roseanna S; Geck, Peter; Isselbacher, Kurt J; Shioda, Toshi.

Proc Natl Acad Sci U S A ; 101(8): 2351-6, 2004 Feb 24.

Artigo em Inglês | MEDLINE | ID: mdl-14983013

19.

Cloning of mouse Cited4, a member of the CITED family p300/CBP-binding transcriptional coactivators: induced expression in mammary epithelial cells.

Yahata, Tetsuro; Takedatsu, Hiroko; Dunwoodie, Sally L; Bragança, José; Swingler, Tracey; Withington, Sarah L; Hur, Jingyung; Coser, Kathryn R; Isselbacher, Kurt J; Bhattacharya, Shoumo; Shioda, Toshi.

Genomics ; 80(6): 601-13, 2002 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-12504852

20.

Harrison internal medicine/Harrison medicina interna

Isselbacher, Kurt J; Braunwald, Eugene; Wilson, Jean D; Martin, Joseph B; Fauci, Anthony S; Kasper, Dennis L.

Mexico; McGraw-Hill; 13; c1994. xxxi,1407-2765 p. il.

Monografia em Português | Instituto Evandro Chagas (SOPHIA) | ID: iec-8533

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Instituto Evandro Chagas

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Molecular signatures of circulating melanoma cells for monitoring early response to immune checkpoint therapy.

Relevance of iPSC-derived human PGC-like cells at the surface of embryoid bodies to prechemotaxis migrating PGCs.

An RNA-based signature enables high specificity detection of circulating tumor cells in hepatocellular carcinoma.

Erasure of DNA methylation, genomic imprints, and epimutations in a primordial germ-cell model derived from mouse pluripotent stem cells.

Expressomal approach for comprehensive analysis and visualization of ligand sensitivities of xenoestrogen responsive genes.

Isolation of circulating tumor cells using a microvortex-generating herringbone-chip.

Antiestrogen-resistant subclones of MCF-7 human breast cancer cells are derived from a common monoclonal drug-resistant progenitor.

Production and Analysis of Human Primordial Germ Cell-Like Cells.

Transcriptomic and Epigenetic Preservation of Genetic Sex Identity in Estrogen-feminized Male Chicken Embryonic Gonads.

Generation of Human Primordial Germ Cell-like Cells at the Surface of Embryoid Bodies from Primed-pluripotency Induced Pluripotent Stem Cells.

Regulation of expression of BIK proapoptotic protein in human breast cancer cells: p53-dependent induction of BIK mRNA by fulvestrant and proteasomal degradation of BIK protein.

Irritable bowel syndrome: the possible benefits of probiotics.

Calprotectin: a predictive marker of a relapse in ulcerative colitis.

Importance of dosage standardization for interpreting transcriptomal signature profiles: evidence from studies of xenoestrogens.

Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib.

Retrospective. Paul C. Zamecnik (1912-2009).

Global analysis of ligand sensitivity of estrogen inducible and suppressible genes in MCF7/BUS breast cancer cells by DNA microarray.

The Bik BH3-only protein is induced in estrogen-starved and antiestrogen-exposed breast cancer cells and provokes apoptosis.

Cloning of mouse Cited4, a member of the CITED family p300/CBP-binding transcriptional coactivators: induced expression in mammary epithelial cells.

Harrison internal medicine/Harrison medicina interna