Detalhe da pesquisa
1.
Discovery, design, and synthesis of indole-based EZH2 inhibitors.
Bioorg Med Chem Lett
; 25(17): 3644-9, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26189078
2.
MicroRNA regulation and its effects on cellular transcriptome in human immunodeficiency virus-1 (HIV-1) infected individuals with distinct viral load and CD4 cell counts.
BMC Infect Dis
; 13: 250, 2013 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23721325
3.
Identification and characterization of genes required for cell-to-cell fusion in Neurospora crassa.
Eukaryot Cell
; 10(8): 1100-9, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21666072
4.
Design and Synthesis of Styrenylcyclopropylamine LSD1 Inhibitors.
ACS Med Chem Lett
; 11(6): 1213-1220, 2020 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32551003
5.
Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymphomas.
J Med Chem
; 59(21): 9928-9941, 2016 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27739677
6.
EZH2 inhibitor efficacy in non-Hodgkin's lymphoma does not require suppression of H3K27 monomethylation.
Chem Biol
; 21(11): 1463-75, 2014 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25457180