Detalhe da pesquisa
1.
FZR1 loss increases sensitivity to DNA damage and consequently promotes murine and human B-cell acute leukemia.
Blood
; 129(14): 1958-1968, 2017 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28143883
2.
Inhibition of translation initiation factor eIF4a inactivates heat shock factor 1 (HSF1) and exerts anti-leukemia activity in AML.
Leukemia
; 35(9): 2469-2481, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34127794
3.
Inhibition of mTORC1/C2 signaling improves anti-leukemia efficacy of JAK/STAT blockade in CRLF2 rearranged and/or JAK driven Philadelphia chromosome-like acute B-cell lymphoblastic leukemia.
Oncotarget
; 9(8): 8027-8041, 2018 Jan 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29487712
4.
Differential regulation of Pyk2 phosphorylation at Tyr-402 and Tyr-580 in intestinal epithelial cells: roles of calcium, Src, Rho kinase, and the cytoskeleton.
Cell Signal
; 18(11): 1932-40, 2006 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16574377
5.
ATF4 induction through an atypical integrated stress response to ONC201 triggers p53-independent apoptosis in hematological malignancies.
Sci Signal
; 9(415): ra17, 2016 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26884599
6.
Reversal of acquired drug resistance in FLT3-mutated acute myeloid leukemia cells via distinct drug combination strategies.
Clin Cancer Res
; 20(9): 2363-74, 2014 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24619500
7.
Synergistic targeting of AML stem/progenitor cells with IAP antagonist birinapant and demethylating agents.
J Natl Cancer Inst
; 106(2): djt440, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24526787
8.
Oxygen sensing mesenchymal progenitors promote neo-vasculogenesis in a humanized mouse model in vivo.
PLoS One
; 7(9): e44468, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22970226
9.
Ganglioside GD2 identifies breast cancer stem cells and promotes tumorigenesis.
J Clin Invest
; 122(6): 2066-78, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22585577
10.
SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancer.
Cancer Cell
; 18(2): 109-21, 2010 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-20708153
11.
A truncated FAK lacking the FERM domain displays high catalytic activity but retains responsiveness to adhesion-mediated signals.
Biochem Biophys Res Commun
; 334(4): 1299-304, 2005 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-16039608
12.
G protein-coupled receptor activation rapidly stimulates focal adhesion kinase phosphorylation at Ser-843. Mediation by Ca2+, calmodulin, and Ca2+/calmodulin-dependent kinase II.
J Biol Chem
; 280(25): 24212-20, 2005 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-15845548