Detalhe da pesquisa
1.
In Vivo and In Vitro Characterization of Close Analogs of Compound KA-11, a New Antiseizure Drug Candidate.
Int J Mol Sci
; 24(9)2023 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37176010
2.
Synthesis, anticonvulsant, and antinociceptive activity of new 3-(3-methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)propanamides and 3-phenyl-butanamides.
Arch Pharm (Weinheim)
; 354(1): e2000225, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-32939789
3.
Identification of New Compounds with Anticonvulsant and Antinociceptive Properties in a Group of 3-substituted (2,5-dioxo-pyrrolidin-1-yl)(phenyl)-Acetamides.
Int J Mol Sci
; 22(23)2021 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34884898
4.
The Search for New Anticonvulsants in a Group of (2,5-Dioxopyrrolidin-1-yl)(phenyl)Acetamides with Hybrid Structure-Synthesis and In Vivo/In Vitro Studies.
Int J Mol Sci
; 21(22)2020 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33233618
5.
TRPV1 channel in the pathophysiology of epilepsy and its potential as a molecular target for the development of new antiseizure drug candidates.
Prog Neurobiol
; 240: 102634, 2024 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38834133
6.
A comprehensive assessment of palmatine as anticonvulsant agent - In vivo and in silico studies.
Biomed Pharmacother
; 172: 116234, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38325264
7.
Novel Alaninamide Derivatives with Drug-like Potential for Development as Antiseizure and Antinociceptive TherapiesâIn Vitro and In Vivo Characterization.
ACS Chem Neurosci
; 15(11): 2198-2222, 2024 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38741575
8.
New Phenylglycinamide Derivatives with Hybrid Structure as Candidates for New Broad-Spectrum Anticonvulsants.
Cells
; 11(12)2022 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35740990
9.
Discovery of (R)-N-Benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide [(R)-AS-1], a Novel Orally Bioavailable EAAT2 Modulator with Drug-like Properties and Potent Antiseizure Activity In Vivo.
J Med Chem
; 65(17): 11703-11725, 2022 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35984707
10.
N-Benzyl-(2,5-dioxopyrrolidin-1-yl)propanamide (AS-1) with Hybrid Structure as a Candidate for a Broad-Spectrum Antiepileptic Drug.
Neurotherapeutics
; 17(1): 309-328, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31486023
11.
Chirality as an Important Factor for the Development of New Antiepileptic Drugs.
ChemMedChem
; 14(20): 1744-1761, 2019 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31476107