Detalhe da pesquisa
1.
Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease.
Proc Natl Acad Sci U S A
; 119(49): e2123487119, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36454749
2.
Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.
EMBO J
; 35(10): 1077-97, 2016 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26951610
3.
CUG initiation and frameshifting enable production of dipeptide repeat proteins from ALS/FTD C9ORF72 transcripts.
Nat Commun
; 9(1): 152, 2018 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29323119
4.
ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS.
Neuron
; 100(4): 816-830.e7, 2018 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-30344044
5.
Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation.
Nat Commun
; 8(1): 45, 2017 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28663553
6.
ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS.
Neuron
; 106(2): 354, 2020 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32325059