Detalhe da pesquisa
1.
Friends or Foes? Emerging Impacts of Biological Toxins.
Trends Biochem Sci
; 44(4): 365-379, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30651181
2.
Development of Bifunctional, Raman Active Diyne-Girder Stapled α-Helical Peptides.
Chemistry
; 29(41): e202300855, 2023 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37130830
3.
Synthesis and Fluorescent Properties of ß-Pyridyl α-Amino Acids.
J Org Chem
; 84(5): 2879-2890, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30726078
4.
A heme-binding domain controls regulation of ATP-dependent potassium channels.
Proc Natl Acad Sci U S A
; 113(14): 3785-90, 2016 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27006498
5.
Urotensin-II peptidomimetic incorporating a non-reducible 1,5-triazole disulfide bond reveals a pseudo-irreversible covalent binding mechanism to the urotensin G-protein coupled receptor.
Org Biomol Chem
; 15(21): 4704-4710, 2017 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28524918
6.
Insights into the Recruitment of Class IIa Histone Deacetylases (HDACs) to the SMRT/NCoR Transcriptional Repression Complex.
J Biol Chem
; 290(29): 18237-18244, 2015 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26055705
7.
Robust asymmetric synthesis of unnatural alkenyl amino acids for conformationally constrained α-helix peptides.
Org Biomol Chem
; 12(43): 8775-82, 2014 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25266495
8.
Rotamer-Controlled Dual Emissive α-Amino Acids.
Org Lett
; 25(31): 5844-5849, 2023 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37506290
9.
Hydrogen-bonded synthetic mimics of protein secondary structure as disruptors of protein-protein interactions.
Curr Top Microbiol Immunol
; 348: 1-23, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-20827522
10.
Investigating the Structure-Activity Relationship of 1,2,4-Triazine G-Protein-Coupled Receptor 84 (GPR84) Antagonists.
J Med Chem
; 65(16): 11270-11290, 2022 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35948061
11.
Hydroxamic Acid-Modified Peptide Library Provides Insights into the Molecular Basis for the Substrate Selectivity of HDAC Corepressor Complexes.
ACS Chem Biol
; 17(9): 2572-2582, 2022 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35973051
12.
Peptides derived from the SARS-CoV-2 receptor binding motif bind to ACE2 but do not block ACE2-mediated host cell entry or pro-inflammatory cytokine induction.
PLoS One
; 16(11): e0260283, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34793553
13.
Stapled ACE2 peptidomimetics designed to target the SARS-CoV-2 spike protein do not prevent virus internalization.
Pept Sci (Hoboken)
; 113(4): e24217, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-33615115
14.
A short peptide that preferentially binds c-MYC G-quadruplex DNA.
Chem Commun (Camb)
; 56(63): 8940-8943, 2020 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32638724
15.
Development of Potent PfCLK3 Inhibitors Based on TCMDC-135051 as a New Class of Antimalarials.
J Med Chem
; 63(17): 9300-9315, 2020 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32787140
16.
Conformationally rigid pyrazoloquinazoline α-amino acids: one- and two-photon induced fluorescence.
Chem Commun (Camb)
; 56(12): 1887-1890, 2020 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31956866
17.
Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun
; 11(1): 2094, 2020 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32350255
18.
Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex.
Cell Rep
; 30(8): 2699-2711.e8, 2020 02 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32101746
19.
Positional scanning for peptide secondary structure by systematic solid-phase synthesis of amino lactam peptides.
J Am Chem Soc
; 131(22): 7917-27, 2009 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19453183
20.
Synthesis of HDAC Substrate Peptidomimetic Inhibitors Using Fmoc Amino Acids Incorporating Zinc-Binding Groups.
Org Lett
; 21(9): 3178-3182, 2019 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30998366