Pesquisa | BVS IEC

Multiple newly identified loci associated with prostate cancer susceptibility.

Eeles, Rosalind A; Kote-Jarai, Zsofia; Giles, Graham G; Olama, Ali Amin Al; Guy, Michelle; Jugurnauth, Sarah K; Mulholland, Shani; Leongamornlert, Daniel A; Edwards, Stephen M; Morrison, Jonathan; Field, Helen I; Southey, Melissa C; Severi, Gianluca; Donovan, Jenny L; Hamdy, Freddie C; Dearnaley, David P; Muir, Kenneth R; Smith, Charmaine; Bagnato, Melisa; Ardern-Jones, Audrey T; Hall, Amanda L; O'Brien, Lynne T; Gehr-Swain, Beatrice N; Wilkinson, Rosemary A; Cox, Angie; Lewis, Sarah; Brown, Paul M; Jhavar, Sameer G; Tymrakiewicz, Malgorzata; Lophatananon, Artitaya; Bryant, Sarah L; Horwich, Alan; Huddart, Robert A; Khoo, Vincent S; Parker, Christopher C; Woodhouse, Christopher J; Thompson, Alan; Christmas, Tim; Ogden, Chris; Fisher, Cyril; Jamieson, Charles; Cooper, Colin S; English, Dallas R; Hopper, John L; Neal, David E; Easton, Douglas F.

Nat Genet ; 40(3): 316-21, 2008 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-18264097

RESUMO

Prostate cancer is the most common cancer affecting males in developed countries. It shows consistent evidence of familial aggregation, but the causes of this aggregation are mostly unknown. To identify common alleles associated with prostate cancer risk, we conducted a genome-wide association study (GWAS) using blood DNA samples from 1,854 individuals with clinically detected prostate cancer diagnosed at

Assuntos

Predisposição Genética para Doença , Neoplasias da Próstata/genética , Locos de Características Quantitativas , Adulto , Idoso , Idoso de 80 Anos ou mais , Algoritmos , Austrália , Estudos de Casos e Controles , Mapeamento Cromossômico , Genótipo , Humanos , Masculino , Pessoa de Meia-Idade , Polimorfismo de Nucleotídeo Único , Reino Unido

RESUMO

Assuntos

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