Contact Failure Identification in Multilayered Media via Artificial Neural Networks and Autoencoders.

The estimation of defects positioning occurring in the interface between different materials is performed by using an artificial neural network modeled as an inverse heat conduction problem. Identifying contact failures in the bonding process of different materials is crucial in many engineering applications, ranging from manufacturing, preventive inspection and even failure diagnosis. This can be modeled as an inverse heat conduction problem in multilayered media, where thermography temperature measurements from an exposed surface of the media are available. This work solves this inverse problem with an artificial neural network that receives these experimental data as input and outputs the thermalphysical properties of the adhesive layer, where defects can occur. An autoencoder is used to reduce the dimension of the transient 1D thermography data, where its latent space represents the experimental data in a lower dimension, then these reduced data are used as input to a fully connected multilayer perceptron network. Results indicate that this is a promising approach due to the good accuracy and low computational cost observed. In addition, by including different noise levels within a defined range in the training process, the network can generalize the experimental data input and estimate the positioning of defects with similar quality.

In situ radiation explains the frequency of dioecious palms on islands.

BACKGROUND AND AIMS: Dioecy has evolved up to 5000 times in angiosperms, despite the potentially high intrinsic costs to unisexuality. Dioecy prevents inbreeding, which is especially relevant on isolated islands when gene pools are small. Dioecy is also associated with certain dispersal traits, such as fruit size and type. However, the influence of dioecy on other life history traits and island distribution remains poorly understood. Here, we test the effect of dioecy on palm (Arecaceae) speciation rates, fruit size and frequency on islands. METHODS: We used phylogenetic comparative methods to estimate the ancestral state of the sexual system and its impact on speciation rates and fruit size. Frequency of sexual systems, effect of insularity on the probability of being dioecious, and phylogenetic clustering of island dioecious vs. mainland species were inferred. Lastly, we determined the interplay of insularity and sexual system on speciation rates. KEY RESULTS: Palms repeatedly evolved different sexual systems (dioecy, monoecy and polygamy) from a hermaphrodite origin. Differences in speciation rates and fruit size among the different sexual systems were not identified. An effect of islands on the probability of the palms being dioecious was also not found. However, we found a high frequency and phylogenetic clustering of dioecious palms on islands, which were not correlated with higher speciation rates. CONCLUSIONS: The high frequency and phylogenetic clustering may be the result of in situ radiation and suggest an 'island effect' for dioecious palms, which was not explained by differential speciation rates. This island effect also cannot be attributed to long-distance dispersal due to the lack of fruit size difference among sexual systems, and particularly because palm dispersal to islands is highly constrained by the interaction between the sizes of fruit and frugivores. Taken together, we suggest that trait flexibility in sexual system evolution and the in situ radiation of dioecious lineages are the underlying causes of the outstanding distribution of palms on islands.

Quantitative genetics of body size evolution on islands: an individual-based simulation approach.

According to the island rule, small-bodied vertebrates will tend to evolve larger body size on islands, whereas the opposite happens to large-bodied species. This controversial pattern has been studied at the macroecological and biogeographical scales, but new developments in quantitative evolutionary genetics now allow studying the island rule from a mechanistic perspective. Here, we develop a simulation approach based on an individual-based model to model body size change on islands as a progressive adaptation to a moving optimum, determined by density-dependent population dynamics. We applied the model to evaluate body size differentiation in the pigmy extinct hominin Homo floresiensis, showing that dwarfing may have occurred in only about 360 generations (95% CI ranging from 150 to 675 generations). This result agrees with reports suggesting rapid dwarfing of large mammals on islands, as well as with the recent discovery that small-sized hominins lived in Flores as early as 700 kyr ago. Our simulations illustrate the power of analysing ecological and evolutionary patterns from an explicit quantitative genetics perspective.

[Relationship between air temperature and dengue incidence: time series study in Minas Gerais, Brazil (2010-2019)]. / Relação entre temperatura do ar e incidência de dengue: estudo de séries temporais em Minas Gerais, Brasil (2010-2019).

Air temperature is a climatic factor that affects the incidence of dengue, with effects varying according to time and space. We investigated the relationship between minimum air temperature and dengue incidence in Minas Gerais, Brazil, and evaluated the influence of socioeconomic and geographic variables on this relationship. This is a time series study with analysis conducted in three distinct stages: modeling using a distributed lag non-linear model, meta-analysis of models obtained, and meta-regression with geographic and socioeconomic data. Minimum temperature was a protective factor at extreme cold temperatures (RR = 0.65; 95%CI: 0.56-0.76) and moderate cold temperatures (RR = 0.71; 95%CI: 0.64-0.79), and a risk factor at moderate hot temperatures (RR = 1.15; 95%CI: 1.07-1.24), but not at extreme hot temperatures (RR = 1.1; 95%CI: 0.99-1.22). Heterogeneity of the models was high (I2 = 60%), which was also observed in meta-regression. Moderate and extreme cold temperatures have a protective effect, while moderate hot temperatures increase the risk. However, minimum air temperature does not explain the variability in the region, not even with the other variables in meta-regression.

A temperatura do ar é um fator climático que afeta a incidência da dengue, com efeitos variando conforme o tempo e o espaço. Investigamos a relação entre a temperatura mínima do ar e a incidência da doença em Minas Gerais, Brasil, e avaliamos a influência de variáveis socioeconômicas e geográficas nessa relação, calculando-se o risco relativo (RR). Este é um estudo de série temporal com análise conduzida em três etapas distintas: modelagem por uso de distributed lag non-linear model (modelos não-lineares distributivos com defasagem), metanálise dos modelos obtidos e metarregressão com dados geográficos e socioeconômicos. A temperatura mínima foi um fator de proteção quando em temperaturas frias extremas (RR = 0,65; IC95%: 0,56-0,76) e moderadas (RR = 0,71; IC95%: 0,64-0,79) e fator de risco em temperaturas de calor moderado (RR = 1,15; IC95%: 1,07-1,24), mas não em extremo (RR = 1,1; IC95%: 0,99-1,22). A heterogeneidade dos modelos foi elevada (I2 = 60%) e essa medida não foi alterada em metarregressão. Temperaturas frias moderadas e extremas causam efeito protetivo, enquanto moderadas quentes aumentam o risco. No entanto, a temperatura mínima do ar não explica nem a variabilidade da região, nem mesmo com as outras variáveis em metarregressão.

La temperatura del aire es un factor climático que afecta la incidencia del dengue, con efectos que varían según el tiempo y el territorio. Investigamos la relación entre la temperatura mínima del aire y la incidencia de la enfermedad en Minas Gerais, Brasil, y evaluamos la influencia de variables socioeconómicas y geográficas en esta relación. Se trata de un estudio de serie temporal cuyo análisis se realiza en tres etapas distintas: modelación mediante el uso de distributed lag non-linear model (modelos distributivos no lineales con retraso), metaanálisis de los modelos obtenidos y metarregresión con datos geográficos y socioeconómicos. La temperatura mínima fue un factor de protección ante temperaturas extremadamente frías (RR = 0,65; IC95%: 0,56-0,76) y moderadas (RR = 0,71; IC95%: 0,64-0,79) y factor de riesgo en temperaturas de calor moderado (RR = 1,15; IC95%: 1,07-1,24), pero no en extremo (RR = 1,1; IC95%: 0,99-1,22). La heterogeneidad de los modelos fue alta (I2 = 60%), y esta medida no se modificó en la metarregresión. Las temperaturas frías moderadas y extremas tienen un efecto protector, mientras que las temperaturas moderadamente altas aumentan el riesgo. Sin embargo, la temperatura mínima del aire no explica la variabilidad de la región, ni siquiera con las demás variables en metarregresión.

Effects of air temperature on the risk of death from COPD in major microregions in Brazil: a time series study.

OBJECTIVE: To evaluate the association between the risk of death from COPD and air temperature events in ten major Brazilian microregions. METHODS: This was a time series analysis of daily COPD deaths and daily mean air temperatures between 1996 and 2017. Using distributed nonlinear lag models, we estimated the cumulative relative risks of COPD mortality for four temperature percentiles (representing moderate and extreme cold and heat events) in relation to a minimum mortality temperature, with a lag of 21 days, in each microregion. RESULTS: Significant associations were found between extreme air temperature events and the risk of death from COPD in the southern and southeastern microregions in Brazil. There was an association of extreme cold and an increased mortality risk in the following microregions: 36% (95% CI, 1.12-1.65), in Porto Alegre; 27% (95% CI, 1.03-1.58), in Curitiba; and 34% (95% CI, 1.19-1.52), in São Paulo; whereas moderate cold was associated with an increased risk of 20% (95% CI, 1.01-1.41), 33% (95% CI, 1.09-1.62), and 24% (95% CI, 1.12-1.38) in the same microregions, respectively. There was an increased COPD mortality risk in the São Paulo and Rio de Janeiro microregions: 17% (95% CI, 1.05-1.31) and 12% (95% CI, 1,02-1,23), respectively, due to moderate heat, and 23% (95% CI, 1,09-1,38) and 32% (95% CI, 1,15-1,50) due to extreme heat. CONCLUSIONS: Non-optimal air temperature events were associated with an increased risk of death from COPD in tropical and subtropical areas of Brazil.

Relação entre temperatura do ar e incidência de dengue: estudo de séries temporais em Minas Gerais, Brasil (2010-2019) / Relationship between air temperature and dengue incidence: time series study in Minas Gerais, Brazil (2010-2019) / Relación entre la temperatura del aire y la incidencia del dengue: estudio de series temporales en Minas Gerais, Brasil (2010-2019)

Resumo A temperatura do ar é um fator climático que afeta a incidência da dengue, com efeitos variando conforme o tempo e o espaço. Investigamos a relação entre a temperatura mínima do ar e a incidência da doença em Minas Gerais, Brasil, e avaliamos a influência de variáveis socioeconômicas e geográficas nessa relação, calculando-se o risco relativo (RR). Este é um estudo de série temporal com análise conduzida em três etapas distintas: modelagem por uso de distributed lag non-linear model (modelos não-lineares distributivos com defasagem), metanálise dos modelos obtidos e metarregressão com dados geográficos e socioeconômicos. A temperatura mínima foi um fator de proteção quando em temperaturas frias extremas (RR = 0,65; IC95%: 0,56-0,76) e moderadas (RR = 0,71; IC95%: 0,64-0,79) e fator de risco em temperaturas de calor moderado (RR = 1,15; IC95%: 1,07-1,24), mas não em extremo (RR = 1,1; IC95%: 0,99-1,22). A heterogeneidade dos modelos foi elevada (I2 = 60%) e essa medida não foi alterada em metarregressão. Temperaturas frias moderadas e extremas causam efeito protetivo, enquanto moderadas quentes aumentam o risco. No entanto, a temperatura mínima do ar não explica nem a variabilidade da região, nem mesmo com as outras variáveis em metarregressão.

Abstract Air temperature is a climatic factor that affects the incidence of dengue, with effects varying according to time and space. We investigated the relationship between minimum air temperature and dengue incidence in Minas Gerais, Brazil, and evaluated the influence of socioeconomic and geographic variables on this relationship. This is a time series study with analysis conducted in three distinct stages: modeling using a distributed lag non-linear model, meta-analysis of models obtained, and meta-regression with geographic and socioeconomic data. Minimum temperature was a protective factor at extreme cold temperatures (RR = 0.65; 95%CI: 0.56-0.76) and moderate cold temperatures (RR = 0.71; 95%CI: 0.64-0.79), and a risk factor at moderate hot temperatures (RR = 1.15; 95%CI: 1.07-1.24), but not at extreme hot temperatures (RR = 1.1; 95%CI: 0.99-1.22). Heterogeneity of the models was high (I2 = 60%), which was also observed in meta-regression. Moderate and extreme cold temperatures have a protective effect, while moderate hot temperatures increase the risk. However, minimum air temperature does not explain the variability in the region, not even with the other variables in meta-regression.

Resumen La temperatura del aire es un factor climático que afecta la incidencia del dengue, con efectos que varían según el tiempo y el territorio. Investigamos la relación entre la temperatura mínima del aire y la incidencia de la enfermedad en Minas Gerais, Brasil, y evaluamos la influencia de variables socioeconómicas y geográficas en esta relación. Se trata de un estudio de serie temporal cuyo análisis se realiza en tres etapas distintas: modelación mediante el uso de distributed lag non-linear model (modelos distributivos no lineales con retraso), metaanálisis de los modelos obtenidos y metarregresión con datos geográficos y socioeconómicos. La temperatura mínima fue un factor de protección ante temperaturas extremadamente frías (RR = 0,65; IC95%: 0,56-0,76) y moderadas (RR = 0,71; IC95%: 0,64-0,79) y factor de riesgo en temperaturas de calor moderado (RR = 1,15; IC95%: 1,07-1,24), pero no en extremo (RR = 1,1; IC95%: 0,99-1,22). La heterogeneidad de los modelos fue alta (I2 = 60%), y esta medida no se modificó en la metarregresión. Las temperaturas frías moderadas y extremas tienen un efecto protector, mientras que las temperaturas moderadamente altas aumentan el riesgo. Sin embargo, la temperatura mínima del aire no explica la variabilidad de la región, ni siquiera con las demás variables en metarregresión.

Effects of air temperature on the risk of death from COPD in major microregions in Brazil: a time series study / Efeitos da temperatura do ar no risco de morte por DPOC nas principais microrregiões do Brasil: um estudo de séries temporais

ABSTRACT Objective: To evaluate the association between the risk of death from COPD and air temperature events in ten major Brazilian microregions. Methods: This was a time series analysis of daily COPD deaths and daily mean air temperatures between 1996 and 2017. Using distributed nonlinear lag models, we estimated the cumulative relative risks of COPD mortality for four temperature percentiles (representing moderate and extreme cold and heat events) in relation to a minimum mortality temperature, with a lag of 21 days, in each microregion. Results: Significant associations were found between extreme air temperature events and the risk of death from COPD in the southern and southeastern microregions in Brazil. There was an association of extreme cold and an increased mortality risk in the following microregions: 36% (95% CI, 1.12-1.65), in Porto Alegre; 27% (95% CI, 1.03-1.58), in Curitiba; and 34% (95% CI, 1.19-1.52), in São Paulo; whereas moderate cold was associated with an increased risk of 20% (95% CI, 1.01-1.41), 33% (95% CI, 1.09-1.62), and 24% (95% CI, 1.12-1.38) in the same microregions, respectively. There was an increased COPD mortality risk in the São Paulo and Rio de Janeiro microregions: 17% (95% CI, 1.05-1.31) and 12% (95% CI, 1,02-1,23), respectively, due to moderate heat, and 23% (95% CI, 1,09-1,38) and 32% (95% CI, 1,15-1,50) due to extreme heat. Conclusions: Non-optimal air temperature events were associated with an increased risk of death from COPD in tropical and subtropical areas of Brazil.

RESUMO Objetivo: Avaliar a associação entre o risco de morte por DPOC e eventos de temperatura do ar em dez grandes microrregiões brasileiras. Métodos: Esta foi uma análise de série temporal de mortes diárias por DPOC e temperaturas médias diárias do ar entre 1996 e 2017. Utilizando modelos de defasagem não linear distribuídos, estimamos os riscos relativos cumulativos de mortalidade por DPOC para quatro percentis de temperatura (representando eventos moderados e extremos de frio e calor) em relação a uma temperatura mínima de mortalidade, com defasagem de 21 dias, em cada microrregião. Resultados: Foram encontradas associações significativas entre eventos extremos de temperatura do ar e o risco de morte por DPOC nas microrregiões Sul e Sudeste do Brasil. Houve associação de frio extremo e aumento do risco de mortalidade nas seguintes microrregiões: 36% (IC 95%, 1,12-1,65), em Porto Alegre; 27% (IC 95%, 1,03-1,58), em Curitiba; e 34% (IC 95%, 1,19-1,52), em São Paulo; enquanto o frio moderado foi associado a um risco aumentado de 20% (IC 95%, 1,01-1,41), 33% (IC 95%, 1,09-1,62) e 24% (IC 95%, 1,12-1,38) nas mesmas microrregiões, respectivamente. Houve aumento do risco de mortalidade por DPOC nas microrregiões de São Paulo e Rio de Janeiro: 17% (IC 95%, 1,05-1,31) e 12% (IC 95%, 1,02-1,23), respectivamente, devido ao calor moderado e 23% (IC 95%, 1,09-1,38) e 32% (IC 95%, 1,15-1,50) devido ao calor extremo. Conclusões: Eventos de temperatura do ar não ideal foram associados a um risco aumentado de morte por DPOC em áreas tropicais e subtropicais do Brasil.

Oral Health Access and Early Caries in Childhood in a Primary Care Service in Southern Brazil: A Cross-Sectional Study

Abstract Objective: To evaluate the prevalence of early childhood caries and its association with Child's Programmatic Action dental visits in a Primary Care Service. Material and Methods: A cross-sectional analytical study was carried out at the Health Centers of the Grupo HospitalarConceição Community Health Service in Porto Alegre, RS, Brazil. Mothers answered a questionnaire containing socioeconomic data, eating habits and oral care of their children. Caries examination was performed by two examiners calibrated using WHO criteria. Results: Eighty-one children with mean age of 58.8 (SD=4.8) months were evaluated, 58% were male. Caries prevalence was 43%, with mean dmft = 1.7 and mean dmfs = 3.09. In the multivariate analysis, there was a statistically significant association of caries with maternal schooling (PR=1.31, 95%CI=1.06-1.62, p=0.012), family income (PR=0.93, 95% CI=0.90-0.97, p<0.001), adequacy of the number of childcare visits (PR=0.68, 95%CI=0.54-0.86, p=0.001) and number of visits to the dentist (PR=1.04, 95%CI=1.01-1.06, p=0.001). Conclusion: Ensuring access to childcare and early dental consultation, while the family context is disregarded, does not seem to be enough to reduce caries. It is necessary to think of non-conventional oral health promotion strategies in Primary Health Care taking into account the territory and social determinants since changes to eating and oral hygiene habits and behaviors are still a challenge to the control of childhood caries.

Prevalência de má oclusão em crianças de quatro anos de idade e fatores associados na Atenção Primária à Saúde / Prevalence of malocclusion in four-year-old children and associated factors in Primary Health Care

Objetivo: avaliar a prevalência de má oclusão em crianças nascidas em 2010 e sua associação com a realização de consultas odontológicas em um serviço de Atenção Primária à Saúde. Métodos: estudo analítico transversal realizado em duas Unidades de Saúde do Serviço de Saúde Comunitária do Grupo Hospitalar. O exame de má oclusão das crianças com 4 anos completos foi realizado por dois dentistas treinados e calibrados, seguido da aplicação do questionário sobre hábitos da criança para o responsável. Os dados de consultas odontológicas foram coletados no Sistema de Informações do GHC. As análises foram feitas no programa SPSS através do teste Qui-quadrado e da Regressão de Poisson, com significância estatística de p<0,05. Resultados: uma amostra consecutiva de 81 crianças com idade média de 58,8 (DP=4,8) meses foi avaliada, sendo 58% do sexo masculino. Do total, 28% das crianças apresentavam mordida aberta anterior, 10% de mordida cruzada posterior e selamento labial não adequado. Uso de chupeta ainda era presente em 22% das crianças. Não houve associação entre má oclusão e número de consultas odontológicas (p=0,837), assim como realização de uma consulta anual até 4 anos de idade (p=0,684). Na análise multivariada, houve associação significativa de má oclusão com uso de chupeta (RP=0,15, IC95%=0,07­0,35), bem como o seu tempo de uso (RP=1,05, IC95%=1.03-1.08). Conclusão: má oclusão na primeira infância está fortemente associada ao uso de chupeta e o acompanhamento precoce pela equipe de saúde bucal pareceu não interferir na cessação do hábito e regressão da oclusopatia aos 4 anos.

Objective: to evaluate the prevalence of malocclusion in children born in 2010 and its association with dental consultations in a primary health care service. Methods: a cross-sectional analytical study carried out in two Health Units of the Grupo Hospitalar Conceição (GHC), Porto Alegre-RS. The malocclusion test of children with 4 years of age was performed by two trained and calibrated dentists, followed by a questionnaire with the person responsible for the child's habits. Data from dental consultations were collected in the GHC Information System. The analyzes were performed in the SPSS program using the Chi-square test and the Poisson regression, with statistical significance of p <0.05. Results: a consecutive sample of 81 children with mean age of 58.8 (SD=4.8) months was evaluated, being 58% male. 28% of the children had anterior open bite, 10% posterior crossbite and inadequate lip sealing. Pacifier use was still present in 22% of children. There was no association between malocclusion and number of dental appointments (p = 0.837), as well as an annual consultation up to 4 years of age (p = 0.684). In the multivariate analysis, there was a significant association of malocclusion with pacifier use (PR = 0.15, 95% CI = 0.07-0.35) as well as its duration of use (PR = 1.05, 95% CI = 1.03- 1.08). Conclusion: malocclusion in early childhood is strongly associated with pacifier use and early follow-up by the oral health team did not seem to interfere with cessation of the habit and regression of occlusion at 4 years.

Saúde bucal de pessoas em situação de pobreza extrema residentes em um município no sul do Brasil / Oral health of people in extreme poverty in a city in southern Brazil

Para proporcionar ações efetivas na busca pela saúde bucal, o acesso à saúde deve ser singularizado conforme as necessidades da população, o que deve ser planejado a partir de levantamentos e estudos que evidenciem o perfil da comunidade e que sirvam de parâmetro para o planejamento de futuras ações. Deste modo, o objetivo foi descrever a condição de saúde bucal de famílias cadastradas na Estratégia Saúde da Família da Unidade Básica de Saúde Augusta Meneguine, no município de Viamão, RS. Foi um estudo transversal, de amostra intencional, constituída por 151 pessoas que foram examinadas durante visitas domiciliares realizadas aos sábados, durante mutirões de saúde interdisciplinares, obtendo os seguintes resultados: 42% das pessoas viviam com até 1 salário mínimo e 48,6% moravam com 3 a 5 pessoas por casa, 50% apresentaram dentes cariados, 85,7% placa visível e 65,7% sangramento gengival, sendo possível identificar um perfil carente de saúde bucal e de nível socioeconômico da população. Os resultados deste estudo poderão nortear a implementação de ações em saúde bucal no município de Viamão, RS, Brasil, contribuindo para o planejamento e a alocação de recursos em políticas públicas de saúde.

To provide effective actions aiming oral health, the access to health must be done according to the needs of the population, through studies on the profile of the community, serving as a parameter for future actions. Thus, the objective of the present study was describe the oral health condition profile of the population registered in the Family Health Program,in Viamão city, RS. A cross-sectional study of a convenience sample consisting of 151 people was performed. The individuals were examined once a week during home visits, obtaining the following results: 42% people living with up to 1 minimum wage; 48.6% with a 3-5 individuals per household; 50% had decayed teeth; 85.7% had visible plaque; and 65.7% had gingival bleeding, thus, evidenciong a poor oral health and socioeconomic status of the population. The results will guide the implementation of oral health practices in the city of Viamão, RS, Brazil, contributing to the planning and resource allocation in public health policies.