Detalhe da pesquisa
1.
Activation of human STING by a molecular glue-like compound.
Nat Chem Biol
; 20(3): 365-372, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37828400
2.
Phenotypic landscape of intestinal organoid regeneration.
Nature
; 586(7828): 275-280, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33029001
3.
Compound Activity Prediction with Dose-Dependent Transcriptomic Profiles and Deep Learning.
J Chem Inf Model
; 64(7): 2695-2704, 2024 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38293736
4.
CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma.
Nat Chem Biol
; 16(1): 50-59, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31819276
5.
Author Correction: CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma.
Nat Chem Biol
; 16(4): 479, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32139909
6.
Acceptance and Commitment Therapy (ACT) Guided Online for Distressed Caregivers of Persons Living with Dementia.
Clin Gerontol
; 45(4): 927-938, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-33794127
7.
Discovery of a ZIP7 inhibitor from a Notch pathway screen.
Nat Chem Biol
; 15(2): 179-188, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30643281
8.
Benchmarking network algorithms for contextualizing genes of interest.
PLoS Comput Biol
; 15(12): e1007403, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31860671
9.
Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide.
Nature
; 512(7512): 49-53, 2014 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25043012
10.
Growth-restricting effects of siRNA transfections: a largely deterministic combination of off-target binding and hybridization-independent competition.
Nucleic Acids Res
; 46(18): 9309-9320, 2018 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30215772
11.
Large-scale prediction and testing of drug activity on side-effect targets.
Nature
; 486(7403): 361-7, 2012 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22722194
12.
Target identification for a Hedgehog pathway inhibitor reveals the receptor GPR39.
Nat Chem Biol
; 10(5): 343-9, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24633354
13.
Ten simple rules to power drug discovery with data science.
PLoS Comput Biol
; 16(8): e1008126, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32853229
14.
Data-Driven Derivation of an "Informer Compound Set" for Improved Selection of Active Compounds in High-Throughput Screening.
J Chem Inf Model
; 56(9): 1622-30, 2016 09 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27487177
15.
Small molecule-facilitated degradation of ANO1 protein: a new targeting approach for anticancer therapeutics.
J Biol Chem
; 289(16): 11029-11041, 2014 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24599954
16.
Using information from historical high-throughput screens to predict active compounds.
J Chem Inf Model
; 54(7): 1880-91, 2014 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-24933016
17.
Pocket Crafter: a 3D generative modeling based workflow for the rapid generation of hit molecules in drug discovery.
J Cheminform
; 16(1): 33, 2024 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38515171
18.
Enhancing the Small-Scale Screenable Biological Space beyond Known Chemogenomics Libraries with Gray Chemical MatterâCompounds with Novel Mechanisms from High-Throughput Screening Profiles.
ACS Chem Biol
; 19(4): 938-952, 2024 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38565185
19.
The feasibility and preliminary effects of a pilot randomized controlled trial: Videoconferencing acceptance and commitment therapy in distressed family caregivers of people with dementia.
J Health Psychol
; 28(6): 554-567, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36591636
20.
Effects of a coach-guided videoconferencing acceptance and commitment therapy intervention combined with psychoeducation on distressed individuals living with spinal cord injury: a preliminary mixed-methods study.
Disabil Rehabil
; 45(4): 644-654, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35156500