Detalhe da pesquisa
1.
2-(4-Methylsulfonylphenyl)pyrimidines as Prospective Radioligands for Imaging Cyclooxygenase-2 with PET-Synthesis, Triage, and Radiolabeling.
Molecules
; 23(11)2018 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30400142
2.
In vitro and in vivo evaluation of (11)C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB1 receptors.
Neuroimage
; 84: 733-41, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24076222
3.
In vivo radioligand binding to translocator protein correlates with severity of Alzheimer's disease.
Brain
; 136(Pt 7): 2228-38, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23775979
4.
Comparison of [(11)C]-(R)-PK 11195 and [(11)C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker.
Neuroimage
; 49(4): 2924-32, 2010 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19948230
5.
Neuroinflammation in frontotemporal lobar degeneration revealed by 11 C-PBR28 PET.
Ann Clin Transl Neurol
; 6(7): 1327-1331, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31353865
6.
Conjugated linoleic acids and CLA-containing phospholipids inhibit NO formation in aortic endothelial cells.
Lipids
; 43(4): 335-42, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18335270
7.
3-Substituted 1,5-Diaryl-1 H-1,2,4-triazoles as Prospective PET Radioligands for Imaging Brain COX-1 in Monkey. Part 1: Synthesis and Pharmacology.
ACS Chem Neurosci
; 9(11): 2610-2619, 2018 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29678105
8.
3-Substituted 1,5-Diaryl-1 H-1,2,4-triazoles as Prospective PET Radioligands for Imaging Brain COX-1 in Monkey. Part 2: Selection and Evaluation of [11C]PS13 for Quantitative Imaging.
ACS Chem Neurosci
; 9(11): 2620-2627, 2018 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29792035
9.
Distinct patterns of increased translocator protein in posterior cortical atrophy and amnestic Alzheimer's disease.
Neurobiol Aging
; 51: 132-140, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28068564
10.
Translocator protein ligands based on N-methyl-(quinolin-4-yl)oxypropanamides with properties suitable for PET radioligand development.
Eur J Med Chem
; 124: 677-688, 2016 Nov 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27622910
11.
(11)C-PBR28 binding to translocator protein increases with progression of Alzheimer's disease.
Neurobiol Aging
; 44: 53-61, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27318133
12.
[carbonyl-11C]4-Fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([11C]FIMX) is an effective radioligand for PET imaging of metabotropic glutamate receptor 1 (mGluR1) in monkey brain.
Nucl Med Biol
; 42(12): 967-74, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26320813
13.
Neuroinflammation in Temporal Lobe Epilepsy Measured Using Positron Emission Tomographic Imaging of Translocator Protein.
JAMA Neurol
; 72(8): 882-8, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26052981
14.
Synthesis and evaluation of translocator 18 kDa protein (TSPO) positron emission tomography (PET) radioligands with low binding sensitivity to human single nucleotide polymorphism rs6971.
ACS Chem Neurosci
; 5(10): 963-71, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25123416
15.
Is metabotropic glutamate receptor 5 upregulated in prefrontal cortex in fragile X syndrome?
Mol Autism
; 4(1): 15, 2013 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23706040
16.
A genetic polymorphism for translocator protein 18 kDa affects both in vitro and in vivo radioligand binding in human brain to this putative biomarker of neuroinflammation.
J Cereb Blood Flow Metab
; 33(1): 53-8, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-22968319
17.
On quantitative relationships between drug-like compound lipophilicity and plasma free fraction in monkey and human.
J Pharm Sci
; 101(3): 1028-39, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-22170327
18.
Radiosynthesis and evaluation of an (18)F-labeled positron emission tomography (PET) radioligand for brain histamine subtype-3 receptors based on a nonimidazole 2-aminoethylbenzofuran chemotype.
J Med Chem
; 55(5): 2406-15, 2012 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22313227
19.
Binding of a tritiated inverse agonist to cannabinoid CB1 receptors is increased in patients with schizophrenia.
Schizophr Res
; 141(2-3): 185-8, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22910406