Detalhe da pesquisa
1.
Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3.
Mar Drugs
; 10(7): 1511-1527, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22851922
2.
Understanding the molecular basis of toxin promiscuity: the analgesic sea anemone peptide APETx2 interacts with acid-sensing ion channel 3 and hERG channels via overlapping pharmacophores.
J Med Chem
; 57(21): 9195-203, 2014 Nov 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25337890
3.
Spider-venom peptides as therapeutics.
Toxins (Basel)
; 2(12): 2851-71, 2010 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22069579
4.
Chemical synthesis and folding of APETx2, a potent and selective inhibitor of acid sensing ion channel 3.
Toxicon
; 54(1): 56-61, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19306891
5.
Scanning mutagenesis of alpha-conotoxin Vc1.1 reveals residues crucial for activity at the alpha9alpha10 nicotinic acetylcholine receptor.
J Biol Chem
; 284(30): 20275-84, 2009 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19447885