Detalhe da pesquisa
1.
Synthesis and biological evaluation of novel 1,2,3,4-tetrahydro-ß-carboline derivatives as potential antibacterial agents.
Bioorg Med Chem Lett
; : 129822, 2024 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38823728
2.
Design, synthesis, and evaluation of formylpiperazine analogs of Ferrostatin-1 as novel improved ferroptosis inhibitors.
Bioorg Med Chem
; 105: 117716, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38608329
3.
Discovery of Novel Marine-Derived Phidiandine/Lipoic Acid Hybrid as a Potential Anti-Atherosclerosis Agent: Design, Synthesis and in Vitro/in Vivo Evaluation.
Chem Biodivers
; 21(2): e202301371, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38069597
4.
New cycloalkyl[b]thiophenylnicotinamide-based α-glucosidase inhibitors as promising anti-diabetic agents: Synthesis, in silico study, in vitro and in vivo evaluations.
Bioorg Med Chem Lett
; 79: 129069, 2023 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36395995
5.
Discovery of marine phidianidine-based Nrf2 activators and their potential against oxLDL- and HG-induced injury in HUVECs.
Bioorg Med Chem Lett
; 95: 129468, 2023 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37689216
6.
Design, synthesis and biological evaluation of marine phidianidine-inspired derivatives against oxidized ldl-induced endothelial injury by activating Nrf2 anti-oxidation pathway.
Bioorg Chem
; 120: 105606, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35045368
7.
Autophagy Induced by a Novel Triazol Derivative Promotes Angiogenesis Through Decreasing Interferon-Inducible Protein 10 Level in Vascular Endothelial Cells.
J Cardiovasc Pharmacol
; 78(1): e136-e146, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34009854
8.
Design, synthesis and biological evaluation of novel (E)-2-benzylidene-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)hydrazine-1-carboxamide derivatives as α-glucosidase inhibitors.
Bioorg Med Chem Lett
; 52: 128413, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34634473
9.
Discovery of new 2-phenyl-1H-benzo[d]imidazole core-based potent α-glucosidase inhibitors: Synthesis, kinetic study, molecular docking, and in vivo anti-hyperglycemic evaluation.
Bioorg Chem
; 117: 105423, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34717239
10.
Novel tetrahydrobenzo[b]thiophen-2-yl)urea derivatives as novel α-glucosidase inhibitors: Synthesis, kinetics study, molecular docking, and in vivo anti-hyperglycemic evaluation.
Bioorg Chem
; 115: 105236, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34411978
11.
Synthesis and evaluation of 1,2,4-oxadiazole derivatives as potential anti-inflammatory agents by inhibiting NF-κB signaling pathway in LPS-stimulated RAW 264.7 cells.
Bioorg Med Chem Lett
; 30(17): 127373, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32738985
12.
A New Endoplasmic Reticulum (ER)-Targeting Fluorescent Probe for the Imaging of Cysteine in Living Cells.
J Fluoresc
; 30(6): 1357-1364, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-32870455
13.
New cembrane-type diterpenoids from the South China Sea soft coral Sinularia crassa and their α-glucosidase inhibitory activity.
Bioorg Chem
; 104: 104281, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32980673
14.
Discovery and Biological Evaluation of New Selective Acetylcholinesterase Inhibitors with Anti-Aß Aggregation Activity through Molecular Docking-Based Virtual Screening.
Chem Pharm Bull (Tokyo)
; 68(2): 161-166, 2020 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31813907
15.
The Development Process: from SAHA to Hydroxamate HDAC Inhibitors with Branched CAP Region and Linear Linker.
Chem Biodivers
; 17(1): e1900427, 2020 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-31793143
16.
Oxidative Dearomative Cross-Dehydrogenative Coupling of Indoles with Diverse C-H Nucleophiles: Efficient Approach to 2,2-Disubstituted Indolin-3-ones.
Molecules
; 25(2)2020 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31968572
17.
Development of hydroxamate-based histone deacetylase inhibitors containing 1,2,4-oxadiazole moiety core with antitumor activities.
Bioorg Med Chem Lett
; 29(1): 15-21, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30455152
18.
Discovery of new multifunctional selective acetylcholinesterase inhibitors: structure-based virtual screening and biological evaluation.
J Comput Aided Mol Des
; 33(5): 521-530, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30989573
19.
Molecular-docking-guided design and synthesis of new IAA-tacrine hybrids as multifunctional AChE/BChE inhibitors.
Bioorg Chem
; 83: 277-288, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30391700
20.
A new lindenane-type sesquiterpenoid lactone from Chloranthus japonicus.
J Asian Nat Prod Res
; 21(4): 377-383, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29338351