Detalhe da pesquisa
1.
The novel bronchodilator navafenterol: a phase 2a, multicentre, randomised, double-blind, placebo-controlled crossover trial in COPD.
Eur Respir J
; 59(4)2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34503985
2.
Navafenterol (AZD8871) in patients with COPD: a randomized, double-blind, phase I study evaluating safety and pharmacodynamics of single doses of this novel, inhaled, long-acting, dual-pharmacology bronchodilator.
Respir Res
; 21(Suppl 1): 102, 2020 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32907566
3.
Navafenterol (AZD8871) in healthy volunteers: safety, tolerability and pharmacokinetics of multiple ascending doses of this novel inhaled, long-acting, dual-pharmacology bronchodilator, in two phase I, randomised, single-blind, placebo-controlled studies.
Respir Res
; 21(Suppl 1): 212, 2020 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32907575
4.
Navafenterol (AZD8871) in patients with mild asthma: a randomised placebo-controlled phase I study evaluating the safety, tolerability, pharmacokinetics, and pharmacodynamics of single ascending doses of this novel inhaled long-acting dual-pharmacology bronchodilator.
Respir Res
; 21(Suppl 1): 211, 2020 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32907576
5.
Abediterol, a novel long-acting ß2-agonist: bronchodilation, safety, tolerability and pharmacokinetic results from a single-dose, dose-ranging, active-comparator study in patients with COPD.
BMC Pulm Med
; 16(1): 102, 2016 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27439370
6.
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose Study to Evaluate the Pharmacokinetics, Immunogenicity, Safety, and Tolerability After Subcutaneous Administration of Tozorakimab in Healthy Chinese Participants.
Clin Pharmacol Drug Dev
; 13(6): 665-671, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38523487
7.
A Randomized Phase I Study of the Anti-Interleukin-33 Antibody Tozorakimab in Healthy Adults and Patients With Chronic Obstructive Pulmonary Disease.
Clin Pharmacol Ther
; 115(3): 565-575, 2024 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38115209
8.
The Pharmacokinetics, Safety and Tolerability of Aclidinium Bromide 400 µg Administered by Inhalation as Single and Multiple (Twice Daily) Doses in Healthy Chinese Participants.
Int J Chron Obstruct Pulmon Dis
; 18: 2725-2735, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38046981
9.
[Analysis of differences in flow-mediated dilation in relation to the treatment of coronary patients]. / Anális de las diferencias encontradas en la dilatación mediada por flugo según la terapia seguida en pacientes con enfermedad coronaria.
Rev Esp Cardiol
; 56(2): 128-36, 2003 Feb.
Artigo
em Espanhol
| MEDLINE | ID: mdl-12605757
10.
First-in-human study of the safety, tolerability, pharmacokinetics and pharmacodynamics of abediterol (LAS100977), a novel long-acting Β2 -agonist.
J Clin Pharmacol
; 54(12): 1347-53, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24989946