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1.
Luminescence ; 39(4): e4737, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38587084

RESUMO

The predominant method for pest control has been the use of pesticides, which have been shown to have detrimental effects on soil, freshwater, and crop quality. Therefore, the development of novel and sustainable crop protection strategies has become increasingly imperative. In this study, a novel orange-red emitting Ba2SrWO6: Sm3+ phosphor was synthesized using the high-temperature solid-state reaction. Under ultraviolet excitation, the phosphors showed obvious emission peaks at 575, 614, and 662 nm. The Ba2SrWO6: Sm3+ was used to fabricate a fluorescence film with polydimethylsiloxane (PDMS), and attracted twice as many insects as the blank control group under 365 nm ultraviolet light. This material holds great potential as a fluorescent agent for insect trapping in the pest control fields of tea, cotton, eggplant, rice, potato, grape, and other agricultural industries. Our findings provide an eco-friendly approach to pest management for the increment of food production.


Assuntos
Luminescência , Óxidos , Samário , Compostos de Cálcio , Titânio
2.
BMC Musculoskelet Disord ; 24(1): 234, 2023 Mar 28.
Artigo em Inglês | MEDLINE | ID: mdl-36978129

RESUMO

BACKGROUND: The ability to walk is crucial for maintaining independence and a high quality of life among older adults. Although gait characteristics have been extensively studied in older adults, most studies have investigated muscle activity in the joints of the trunk or the lower limbs without assessing their interactions. Thus, the causes of altered trunk and lower limb movement patterns in older adults remain to explore. Therefore, this study compared the joint kinematic parameters of both trunk and lower limbs between young and older adults to identify kinematic factors associated with changes in gait among older adults. METHODS: In total, 64 older (32 males, aged 68.34 ± 7.38 years; 32 females, aged 67.16 ± 6.66 years) and 64 young (32 males, aged 19.44 ± 0.84 years; 32 females, aged 19.69 ± 0.86 years) healthy adults participated in this study. The range of motion (ROM) of the thorax, pelvis, and trunk in the horizontal plane and of the hip, knee, and ankle joints of the lower limbs in the sagittal plane were measured using a motion capture system with wearable sensors. Two-way analysis of variance assessed differences in ROM by group, sex, and spatio-temporal gait parameters; Pearson correlation analysis assessed the correlation of the trunk and lower limbs. RESULTS: Step length, gait speed, and stride length were greater in young adults (p < 0.001) than in older adults, but older women displayed the fastest gait speed (p < 0.05). ROM values for the pelvis, thorax, trunk, knee joint, and ankle joint of young adults were greater (p < 0.05) than those in older adults. However, hip ROM in older adults was significantly greater than that in young adults (p < 0.05). CONCLUSION: With increasing age, ROM of the lower limbs, especially the ankle joint, decreased significantly, resulting in a significant decrease in gait speed. As ROM of the pelvis decreased, stride length decreased significantly in older adults, who compensate through thoracic rotation. Thus, older adults should enhance muscle strength and increase ROM to improve gait patterns.


Assuntos
Marcha , Qualidade de Vida , Masculino , Adulto Jovem , Humanos , Feminino , Idoso , Marcha/fisiologia , Joelho , Articulação do Joelho/fisiologia , Amplitude de Movimento Articular , Fenômenos Biomecânicos/fisiologia
3.
Mol Genet Genomics ; 290(5): 1885-97, 2015 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-25893419

RESUMO

Influenza A viruses can cause localized outbreaks and worldwide pandemics, owing to their high transmissibility and wide host range. As such, they are among the major diseases that cause human death. However, the molecular changes induced by influenza A virus infection in lung tissue are not entirely clear. Changes in microRNA (miRNA) expression occur in many pathological and physiological processes, and influenza A virus infection has been shown to alter miRNA expression in cultured cells and animal models. In this study, we mined key miRNAs closely related to influenza A virus infection and explored cellular regulatory mechanisms against influenza A virus infection, by building networks among miRNAs and genes, gene ontologies (GOs), and pathways. In this study, miRNAs and mRNAs induced by H1N1 influenza virus infection were measured by gene chips, and we found that 82 miRNAs and 3371 mRNAs were differentially expressed. The 82 miRNAs were further analyzed with the series test of cluster (STC) analysis. Three of the 16 cluster profiles identified by STC, which include 46 miRNAs in the three profiles, changed significantly. Using potential target genes of the 46 miRNAs, we looked for intersections of these genes with 3371 differentially expressed mRNAs; 719 intersection genes were identified. Based on the GO or KEGG databases, we attained GOs or pathways for all of the above intersection genes. Fisher's and χ (2) test were used to calculate p value and false discovery rate (FDR), and according to the standard of p < 0.001, 241 GOs and 76 pathways were filtered. Based on these data, miRNA-gene, miRNA-GO, and miRNA-pathway networks were built. We then extracted three classes of GOs (related to inflammatory and immune response, cell cycle, proliferation and apoptosis, and signal transduction) to build three subgraphs, and pathways strictly related with H1N1 influenza virus infection were filtered to extract a subgraph of the miRNA-pathway network. Last, according to the pathway analysis and miRNA-pathway network analysis, 17 miRNAs were found to be associated with the "influenza A" pathway. This study provides the most complete miRNAome profiles, and the most detailed miRNA regulatory networks to date, and is the first to report the most important 17 miRNAs closely related with the pathway of influenza A. These results are a prelude to advancements in mouse H1N1 influenza virus infection biology and the use of mice as a model for human H1N1 influenza virus infection studies.


Assuntos
Perfilação da Expressão Gênica , Vírus da Influenza A Subtipo H1N1/isolamento & purificação , Pulmão/virologia , MicroRNAs/genética , Animais , Feminino , Redes Reguladoras de Genes , Pulmão/patologia , Masculino , Camundongos , Camundongos Endogâmicos ICR , Análise de Sequência com Séries de Oligonucleotídeos , Reação em Cadeia da Polimerase em Tempo Real
4.
Sheng Li Ke Xue Jin Zhan ; 45(5): 337-42, 2014 Oct.
Artigo em Zh | MEDLINE | ID: mdl-25764792

RESUMO

This review focuses on the benefits of regular physical activity participation have mainly focused on cognitive functioning, anxiety and depression, and self-concept. It is well documented that ex- ercise can enhance cognitive functioning, improve executive function at old age, and improve mental abil- ity of children labeled as educational subnormal or disability. Regular exercise has been used to reduce stress and ward off anxiety and feelings of depression. In addition, exercise can improve self-esteem and positive outlook in life. Studies in these three main areas were reviewed and issues and future directions were highlighted.


Assuntos
Cognição , Exercício Físico , Ansiedade , Depressão , Humanos , Saúde Mental , Autoimagem
5.
Dalton Trans ; 53(9): 4214-4221, 2024 Feb 27.
Artigo em Inglês | MEDLINE | ID: mdl-38328962

RESUMO

Recently, short-wave infrared (SWIR) phosphor-converted light-emitting diodes (pc-LEDs) have garnered increased attention due to their widespread applications in night vision, biological imaging, and non-destructive testing. Nevertheless, the currently used SWIR phosphors suffer from poor thermal stability and low quantum efficiency. In this study, a finely tuned spinel-based solid solution, Mg0.5Zn0.5Ga2O4, is prepared to host Ni2+ to induce SWIR emission. Cr3+ is codoped as a sensitizer to bridge Cr3+ and Ni2+ ions, significantly enhancing blue light absorption and facilitating energy transfer (ET) to Ni2+ ions. The champion SWIR phosphor exhibits a broadband emission centered at 1304 nm with a full width at half maximum (FWHM) of 250 nm, achieving a near-unity internal quantum efficiency (IQE = 97.7%) and a good thermal stability (70.7%@423 K). The fabricated SWIR pc-LED device delivers a high SWIR output power of 39.9 mW at 360 mA, enabling its application in non-destructive imaging and testing.

6.
ACS Appl Mater Interfaces ; 16(23): 30185-30195, 2024 Jun 12.
Artigo em Inglês | MEDLINE | ID: mdl-38818828

RESUMO

Broadband near-infrared (NIR) phosphor-converted light-emitting diodes (pc-LEDs) hold promising potential as next-generation compact, portable, and intelligent NIR light sources. Nonetheless, the lack of high-performance broadband NIR phosphors with an emission peak beyond 900 nm has severely hindered the development and widespread application of NIR pc-LEDs. This study presents a strategy for precise control of energy-state coupling in spinel solid solutions composed of MgxZn1-xGa2O4 to tune the NIR emissions of Cr3+ activators. By combining crystal field engineering and heavy doping, the Cr3+-Cr3+ ion pair emission from the 4T2 state is unlocked, giving rise to unusual broadband NIR emission spanning 650 and 1400 nm with an emission maximum of 913 nm and a full width at half-maximum (fwhm) of 213 nm. Under an optimal Mg/Zn ratio of 4:1, the sample achieves record-breaking performance, including high internal and external quantum efficiency (IQE = 83.9% and EQE = 35.7%) and excellent thermal stability (I423 K/I298 K = 75.8%). Encapsulating the as-obtained phosphors into prototype pc-LEDs yields an overwhelming NIR output power of 124.2 mW at a driving current of 840 mA and a photoelectric conversion efficiency (PCE) of 10.5% at 30 mA, rendering high performance in NIR imaging applications.

7.
Yao Xue Xue Bao ; 48(8): 1241-6, 2013 Aug.
Artigo em Zh | MEDLINE | ID: mdl-24187830

RESUMO

In order to discover the mechanism of Xuebijing oral effervescent tablet (XBJOET) to treat infectious diseases, the effect of XBJOET on endotoxin induced rabbit fever and disseminated intravascular coagulation (DIC) was investigated. Auricle microcirculation in rabbit was detected by laser speckle blood perfusion imager system; coagulation function was measured by coagulation analyzer, fibrinolytic system was quantified by Elisa assay and micro thrombosis in tissues was observed with HE staining under light microscope. The results demonstrated that the body temperature of rabbit decreased significantly at 1-3 h after administration with 4.8, 2.4 and 1.2 g x kg(-1) XBJOET to endotoxin induced DIC rabbit model, the auricle microcirculation blood flow in model group (54.45 +/- 14.53) PU was lower than that in control group (77.18 +/- 12.32) PU. The auricle microcirculation blood flow increased markedly and there was significant difference between model group and 1.2 g x kg(-1) XBJOET group. There was significant difference between model group and control group in the content of PAI1 and FIB. The PAI1 levels in model and control groups were (30.48 +/- 2.46) ng x mL(-1) and (20.93 +/- 3.25) ng x mL(-1), respectively. The FIB levels in model and control group were (3.34 +/- 1.09) g x L(-1) and (4.84 +/- 1.10) g x L(-1), respectively. The content of PAI1 in rabbit plasma decreased notably, there were significant differences between model group and 4.8, 2.4 g x kg(-1) XBJOET groups. On the contrary the content of FIB increased. XBJOET possessed pharmacological activities of curing infectious fever and DIC, the mechanism of which is related to amelioration of microcirculation disturbance, inhibition of fibrinolytic system activation and coagulation and micro thrombosis elimination.


Assuntos
Coagulação Intravascular Disseminada/sangue , Medicamentos de Ervas Chinesas/farmacologia , Febre/fisiopatologia , Administração Oral , Animais , Coagulação Sanguínea/efeitos dos fármacos , Temperatura Corporal/efeitos dos fármacos , Coagulação Intravascular Disseminada/induzido quimicamente , Medicamentos de Ervas Chinesas/administração & dosagem , Pavilhão Auricular/irrigação sanguínea , Endotoxinas , Feminino , Febre/induzido quimicamente , Febre/tratamento farmacológico , Fibrinogênio/metabolismo , Masculino , Microcirculação , Tempo de Tromboplastina Parcial , Inibidor 1 de Ativador de Plasminogênio/sangue , Tempo de Protrombina , Coelhos , Comprimidos , Trombose/patologia
8.
Nanoscale ; 15(33): 13628-13634, 2023 Aug 25.
Artigo em Inglês | MEDLINE | ID: mdl-37526988

RESUMO

All-inorganic metal halide perovskite (MHP) materials have been widely studied because of their unique optoelectronic properties, whereas there has been little research reported on their X-ray afterglow imaging properties. Herein, we report the design and synthesis of Mn2+-doped hexagonal CsCdCl3 MHP crystals with excellent X-ray scintillation and X-ray induced afterglow. The orange emission from Mn2+ shows a red shift due to the strong interaction of the Mn2+-Mn2+ dimers formed at higher doping concentrations. The high-energy X-rays with higher electron filling capacity to feed the shallow (0.71 eV) and deep (0.90-1.08 eV) traps enable a long orange afterglow for more than 300 min. The afterglow emission can be rejuvenated effectively by 870 nm stimulus or heating even after 72 h of decay. Finally, we demonstrate the proof-of-concept applications of the fabricated flexible scintillator films for real-time online X-ray imaging with a spatial resolution of 12.2 lp mm-1, as well as time-lapse X-ray imaging recorded by a cell phone, which shows promise for being able to do offline late-time detection of X-ray afterglow imaging in the future.

9.
ACS Appl Mater Interfaces ; 15(10): 13186-13194, 2023 Mar 15.
Artigo em Inglês | MEDLINE | ID: mdl-36877169

RESUMO

The advent of near-infrared (NIR) afterglow in Cr3+-doped materials has stimulated considerable interest in technological applications owing to the sustainable emission of light with good penetrability. However, the development of Cr3+-free NIR afterglow phosphors with high efficiency, low cost, and precise spectral tunability is still an open question. Herein, we report a novel Fe3+-activated NIR long afterglow phosphor composed of Mg2SnO4 (MSO), in which Fe3+ ions occupy the tetrahedral [Mg-O4] and octahedral [Sn/Mg-O6] sites, giving rise to a broadband NIR emission spanning 720-789 nm. On account of energy-level alignment, the electrons released from the traps show a preferential return to the excited energy level of Fe3+ in tetrahedral sites through tunneling, leading to a single-peak NIR afterglow centered at 789 nm with a full-width at half-maximum (fwhm) of 140 nm. The high-efficiency NIR afterglow, showing a record persistent time lasting over 31 h among Fe3+-based phosphors, is demonstrated as a self-sustainable light source for night vision applications. This work not only provides a novel Fe3+-doped high-efficiency NIR afterglow phosphor for technological applications but also establishes practical guidance for rational tuning of afterglow emissions.

10.
Yao Xue Xue Bao ; 47(7): 904-8, 2012 Jul.
Artigo em Zh | MEDLINE | ID: mdl-22993855

RESUMO

This study is to investigate the treatment of Jin Chai antiviral capsule for influenza virus FM1/47 (H1N1) infection. The model of pneumonia was established by dropping influenza virus into the nose of normal mice, real-time PCR and Western blot technique were used to detect the virus load and the interferoninducible transmembrane protein3 (IFITM3) in lung of mice at the 1st day, 3rd day, 5th day and 7th day after affected. The results showed that Jin Chai antiviral capsule in large, middle, small dose groups can decrease virus load significantly at each time point, after being affected (P<0.05, P<0.01), Jin Chai antiviral capsule can increase the interferoninducible transmembrane protein3 in lung of mice, large dose groups are significantly higher in expression of IFITM3 compared with model group at each time point (P<0.05, P<0.01). Middle dose groups are significantly higher in expression of IFITM3 compared with model group at the 3th day and the 5th day (P<0.05), small dose groups are significantly higher in expression of IFITM3 compared with model group at the 3th day (P<0.05). It can be concluded that Jin Chai antiviral capsule exerts antiviral effects against influenzavirus by raised expression of IFITM3.


Assuntos
Antivirais/farmacologia , Medicamentos de Ervas Chinesas/farmacologia , Proteínas de Membrana/metabolismo , Infecções por Orthomyxoviridae/metabolismo , Pneumonia/metabolismo , Animais , Antivirais/administração & dosagem , Cápsulas , Relação Dose-Resposta a Droga , Combinação de Medicamentos , Medicamentos de Ervas Chinesas/administração & dosagem , Feminino , Vírus da Influenza A Subtipo H1N1/efeitos dos fármacos , Pulmão/metabolismo , Masculino , Camundongos , Camundongos Endogâmicos ICR , Infecções por Orthomyxoviridae/virologia , Plantas Medicinais/química , Pneumonia/virologia , Carga Viral/efeitos dos fármacos
11.
J Colloid Interface Sci ; 624: 725-733, 2022 Oct 15.
Artigo em Inglês | MEDLINE | ID: mdl-35696790

RESUMO

Metal halide perovskites (MHPs) have sparked ongoing research interest due to their high-performance optoelectronic properties. However, blue-light excitable near-infrared (NIR) emitting MHPs is still inaccessible and the achievement of robust thermal-quenching resistance so far remains a huge challenge. In this work, we report on the synthesis of lead-free all-inorganic Mn2+-based perovskite-like single crystals using the designed nonstoichiometric precursor ratio. The special crystal structure endows Mn2+ with efficient blue light excitation and red emission, which enables the capabilities of a good matching with commercial blue LED chips and an efficient sensitization for Ln3+ emitters. The incorporations of Yb3+, Er3+, and Ho3+ functionalize the CsMnCl3 single crystals with multiple NIR emissions by virtue of feeding the energy from Mn2+ to Ln3+ via multi-channels. Most remarkable is the achievement of the robust thermal-quenching resistance, exhibiting (near-) zero-thermal-quenching and even anti-thermal quenching, of the Ln3+ NIR emissions above room temperature. Finally, as a proof-of-concept study, a prototype of an NIR-LED device was fabricated. This work not only provides a general strategy to unlock the blue-light excitable NIR emission from f-f transitions of Ln3+ ions, and a fundamental understanding of the sensitization-activation mechanisms in Ln3+-functionalized manganese (Ⅱ)-based perovskite-like phosphor, but also endows the MHPs with optical functionalities for the future high-potential applications, such as NIR phosphor-converted LEDs, and optical telecommunication.


Assuntos
Elementos da Série dos Lantanídeos , Compostos de Cálcio , Elementos da Série dos Lantanídeos/química , Luz , Óxidos , Titânio
12.
PeerJ ; 10: e14520, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36569999

RESUMO

Aim: The aim of this cross-sectional study was to explore the influence of long-term participating in amateur sports on body posture of school students. Methods: A survey on sport participation was conducted on 1,658 volunteer students aged from 6 to 17 years in two primary schools and one meddle school in Tianjin city. The PA200LE body posture evaluation system and a SpineScanSH-115 electronic spine measuring instrument were used to assess the participants' body posture. According to the survey results and against the inclusion and exclusion criteria, 1,124 eligible participants were divided into seven sport participation groups and seven age-matched control groups for statistical comparisons. Results: Compared with the age-matched controls, the natural standing thoracic kyphosis angle of the swimming group (35.0 ± 9.5 VS 31.2 ± 8.5; t =  - 2.560; p = 0.011) and the football group (34.6 ± 7.2 VS 31.9 ± 7.5; t =  - 2.754; p = 0.006) were found to be significantly larger; the natural standing lumbar lordosis angle (-23.0 ± 11.0 VS -27.0 ± 11.1; t = 0.344; p = 0.024) and the upright sitting lumbar lordosis angle (-11.7 ± 8.4 VS -15.2 ± 12.3; t = 5.738; p = 0.030) of the swimming group was significantly smaller; the upright sitting thoracic kyphosis angle of the running group (25.1 ± 9.3 VS 22.6 ± 9.9; t =  - 1.970; p = 0.050) was significantly larger; the upright sitting thoracic kyphosis angle (23.9 ± 8.9 VS 27.0 ± 7.6; t = 2.096; p = 0.038), the learning position thoracic kyphosis angle (31.0 ± 8.6 VS 37.1 ± 8.9; t = 3.076; p = 0.003), the shoulder level (-1.3 ± 2.1 VS 0.0 ± 2.5; t = 2.389; p = 0.019) and waist level (-1.2 ± 1.7 VS -0.3 ± 1.7; t = 2.511; p = 0.013) of the table tennis group were significantly smaller. Conclusions: The results showed that long-term participation in recreational sports training had an impact on the physical posture of adolescents.


Assuntos
Cifose , Lordose , Humanos , Adolescente , Estudos Transversais , Postura , Natação
13.
ACS Appl Mater Interfaces ; 14(3): 4265-4275, 2022 Jan 26.
Artigo em Inglês | MEDLINE | ID: mdl-35025207

RESUMO

Broadband shortwave infrared (SWIR) light-emitting diodes (LEDs), capable of advancing the next-generation solid-state smart invisible lighting technology, have sparked tremendous interest and will launch ground-breaking spectroscopy and instrumental applications. Nevertheless, the device performance is still suppressed by the low quantum efficiency and limited emission bandwidth of the critical phosphor layer. Herein, we report a high-performance Ni2+-doped garnet solid-solution broadband SWIR emitter centered at ∼1450 nm with a large full-width at half-maximum of ∼300 nm, thereby fabricating, for the first time, a directly excited Ni2+-doped garnet solid-solution phosphor-converted broadband SWIR LED device. A synergetic enhancement strategy, adding a fluxing agent and a charge compensator simultaneously, is proposed to deliver a more than 20-fold increase of the SWIR emission intensity and nearly 2-fold improvement of the thermal quenching behavior. The site occupation and mechanism behind the synergetic enhancement strategy are elucidated by a combination of experimental study and theoretical calculation. A prototype of the SWIR LED with a radiation flux of 1.25 mW is fabricated and utilized as an invisible SWIR light source to demonstrate the SWIR spectroscopy applications. This work not only opens a window to explore novel broadband SWIR phosphors but also provides a synergetic strategy to remarkably improve the performance of artificial SWIR LED light sources.

14.
Yao Xue Xue Bao ; 46(6): 650-5, 2011 Jun.
Artigo em Zh | MEDLINE | ID: mdl-21882524

RESUMO

This study is to investigate the treatment of YinQiaojiedu soft capsule for influenza virus A/PR8/34 (H1N1) infection. The model of pneumonia was established by dropping influenza virus into the nose of normal mice, and the lung index and death rate were observed. Real time RT-PCR and Western blotting technique were used to detect the virus load and the relative expression of M1 protein in lungs of mice on the 1st, 3rd, 5th and 7th day after infection. The results showed that YinQiaojiedu soft capsule in 1 g x kg(-1) and 0.5 g x kg(-1) dose groups can decrease the lung index significantly on the 3rd, 5th and 7th day after being infected (P < 0.05, P < 0.01), and the number of death in the two groups of animals decreased significantly. YinQiaojiedu soft capsule in 1 g x kg(-1) dose group can decreased virus load at each time point, and lower it in 0.5 g x kg(-1) dose group at the 3rd, 5th and 7th day (P < 0.05, P < 0.01). YinQiaojiedu soft capsule can decrease the relative expression of M1 protein in lungs of mice, 1 g x kg(-1) and 0.5 g x kg(-1) dose groups are significantly lower in expression of M1 protein compared with model group at the 3rd and 7th day (P < 0.05, P < 0.01). It can be concluded that YinQiaojiedu soft capsule exerts antiviral effects against influenza virus by downregulating expression of virus load and M1 protein.


Assuntos
Antivirais/farmacologia , Medicamentos de Ervas Chinesas/farmacologia , Infecções por Orthomyxoviridae/tratamento farmacológico , Pneumonia/metabolismo , Carga Viral/efeitos dos fármacos , Proteínas da Matriz Viral/metabolismo , Animais , Antivirais/administração & dosagem , Cápsulas , Medicamentos de Ervas Chinesas/administração & dosagem , Feminino , Vírus da Influenza A Subtipo H1N1 , Pulmão/metabolismo , Pulmão/virologia , Masculino , Camundongos , Camundongos Endogâmicos ICR , Infecções por Orthomyxoviridae/metabolismo , Infecções por Orthomyxoviridae/virologia , Pneumonia/virologia
15.
Zhongguo Zhong Yao Za Zhi ; 36(14): 1845-9, 2011 Jul.
Artigo em Zh | MEDLINE | ID: mdl-22016945

RESUMO

Qingkailing injection, Shuanghuanglian injection, baicalin, chlorogenic acid as sample, guinea pig as control, to observe the specificity of allergic response to traditional Chinese medicine (TCM) injection in BN rats and establish a suitable animal model to evaluate applicability of allergic response in BN rats and guinea pigs induced by TCM. BN rats were sensitized by TCM injection, the symptoms, the rate and degree of allergic response were observed, the level of histamine in serum and tissues were determined by ELISA assay, the rate and degree of pathological changes in target organs were observed by HE staining under light microscope. There were significant symptoms of allergic response can be in BN rats, the level of histamine in serum, lung and trachea tissues increased significantly and there were significant pathological changes in lungs and tracheas. Meanwhile, the similar symptoms of allergic response can be induced by penicillin and trichosanthin. The rate and degree of allergic response, the rate and degree of pathological changes was higher in BN rats than in guinea pigs. Compared with guinea pig, BN rat is probably more suitable animal model in evaluating allergic response to injection of TCM.


Assuntos
Modelos Animais de Doenças , Hipersensibilidade a Drogas , Medicamentos de Ervas Chinesas/administração & dosagem , Medicamentos de Ervas Chinesas/efeitos adversos , Hipersensibilidade Imediata/induzido quimicamente , Animais , Cobaias , Injeções , Masculino , Medicina Tradicional Chinesa , Ratos , Ratos Endogâmicos BN
16.
Huan Jing Ke Xue ; 42(2): 786-795, 2021 Feb 08.
Artigo em Zh | MEDLINE | ID: mdl-33742873

RESUMO

To explore the effects of straw mulching and reduced nitrogen fertilization on the temporal and spatial patterns of soil nitrogen, groundwater nitrogen pollution, and summer maize yield, field experiments were carried out in the Hetao irrigation district in 2017 and 2018. The experiment involved the following seven treatments:a control (CK) treatment involving conventional fertilization and traditional tillage, and conventional nitrogen applications reduced by 30% (N1), 20% (N2), and 10% (N3) coupled with either straw surface covering (B) or deep straw burial (S). The results showed that the distribution of soil nitrogen in the CK treatment varied depending on soil depth, with an overall decreasing trend. In the 0-20 cm soil layer under straw surface covering (B) treatments, soil nitrogen was superficially accumulated. NO3--N and NH4+-N content increased by an average of 22.2% and 42.7% compared to the CK treatment, respectively, which decreased significantly at first and then increased slightly with depth. In the 20-40 cm deep soil layer under the deep straw burial (S) treatments, soil nitrogen accumulated and the content of NO3--N and NH4+-N increased by an average of 29.8% and 48.1%, respectively, compared to the CK treatment. Nitrogen accumulation first and then decreased significantly with depth. Nitrogen accumulation under the different straw mulching regimes increased with an increase in the application of reduced nitrogen. After the harvest of summer maize, the accumulation of NO3--N and NH4+-N in the >80 cm soil layer under the B treatments was 19.9%-58.2% and 31.1%-61.7% lower than that of the CK treatment, respectively. This compared to reductions of 36.7%-70.9% and 82.6%-89.2% for the S treatments, respectively. Only the BN3 treatment increased accumulation compared with CK by 0.4% on average, while the SN2 treatment resulted in a 9.3% increase. Summer maize yield and relative indexes were also improved relative to the other treatments. Nonlinear fitting of yield and application reduction showed that deep straw burial was better than surface covering at increasing summer maize production. The effect of deep straw burial and 14%-20% application reduction was better. Straw mulching with reduced nitrogen fertilization can limit nitrogen leaching and thereby reduce the risk of groundwater pollution. After the harvest, groundwater quality was classified in the Ⅱ class, with the risk of nitrogen contamination being lowest under deep straw burial with>20% reduced nitrogen fertilization. These observations show that deep straw deep alongside 14%-20% application reduction could effectively alleviate nitrogen leaching and reduce the risk of nitrogen pollution in groundwater. This approach can help improve the ecological environment and summer maize yields in the Hetao irrigation district.

17.
Yao Xue Xue Bao ; 45(3): 399-402, 2010 Mar.
Artigo em Zh | MEDLINE | ID: mdl-21351520

RESUMO

It is to investigate the effect of two kinds of Houttuynia Cordata Injection on preventing and treating H1N1 influenza virus infection in mice. Pneumonia model was set up by intranasal infection of the normal and immunocompromised mice with influenza virus FM1 and PR8. The two injections were administered before and after the administration of virus, separately, and the lung index was observed. The results showed that the two preparations have obvious therapeutic effect on normal mice infected with influenza virus FM1 and PR8. And to FM1, the new injection's effect is better at small dosage. The results also showed that the two preparations have obvious prophylactic effect on immunodepressed mice infected with influenza virus FM1 and PR8. And to PR8, the old injection's effect is better at small dosage. Houttuynia Cordata Injection can improve the mice pneumonia caused by influenza virus H1N1 and decrease the lung index markedly. It has a remarkable preventive and therapeutic effect on H1N1 influenza virus in mice.


Assuntos
Medicamentos de Ervas Chinesas/uso terapêutico , Houttuynia/química , Hospedeiro Imunocomprometido , Vírus da Influenza A Subtipo H1N1/efeitos dos fármacos , Infecções por Orthomyxoviridae/tratamento farmacológico , Pneumonia Viral/tratamento farmacológico , Animais , Antivirais/administração & dosagem , Antivirais/uso terapêutico , Medicamentos de Ervas Chinesas/administração & dosagem , Medicamentos de Ervas Chinesas/isolamento & purificação , Feminino , Vírus da Influenza A Subtipo H1N1/imunologia , Injeções , Masculino , Camundongos , Camundongos Endogâmicos ICR , Infecções por Orthomyxoviridae/complicações , Infecções por Orthomyxoviridae/imunologia , Infecções por Orthomyxoviridae/prevenção & controle , Plantas Medicinais/química , Pneumonia Viral/etiologia , Pneumonia Viral/prevenção & controle , Distribuição Aleatória
18.
Sci Rep ; 10(1): 21082, 2020 12 03.
Artigo em Inglês | MEDLINE | ID: mdl-33273593

RESUMO

To provide an appropriate tillage fertilization model for improving N utilization efficiency and increasing production, the field experiments were conducted to study the effects on root distributions and N utilization efficiency of summer maize involving different straw mulching modes combined with N fertilization. No (N0), low (N1), medium (N2), and high (N3) levels of N fertilization were incorporated into soil combined with the surface coverage straw (Treatment B) and the deeply buried straw (Treatment S). The traditional cultivation was used as control treatment. The results shown that treatments S had significantly promoted deep root growth, and the root length density (RLD) increased with increases in N application rate. SN2 and SN3 treatments' average RLD were significantly increased by 67.5% and 68.1% in the greater than 40 cm soil layers. While the Treatment B had significantly increased the RLD in 0 -30 cm soil layers only. With increases in N application rate, the effect on summer maize yields increase under Treatment B were not significantly, and only BN3 increased by 0.4%, while under Treatments S were found to first increase, and then decrease. The apparent recovery efficiency of applied N, N uptake and summer maize yield of SN2 had increased by 66.8%, 20.4%, and 9.3%. Therefore the rational tillage fertilization model was deeply buried straw combined with medium N fertilizer in Hetao Irrigation District.


Assuntos
Produção Agrícola/métodos , Nitrogênio/metabolismo , Zea mays/fisiologia , Fertilizantes , Raízes de Plantas/metabolismo , Raízes de Plantas/fisiologia , Estações do Ano , Zea mays/metabolismo
19.
Chem Asian J ; 14(9): 1506-1514, 2019 May 02.
Artigo em Inglês | MEDLINE | ID: mdl-30825361

RESUMO

Near-infrared (NIR) long-persistent phosphors (LPPs) have emerged as a potential solution for bio-imaging applications over the past few years. However, there are enormous challenges regarding their in situ application based on their dependence on short-wavelength excitation. In this paper, we report a multi-spectral excited NIR LPP, Li5 Zn8 Ga5 Ge9 O36 : 1.5 % Cr3+ , 0.5 % Ti4+ , which overcomes the limitations of functional processes in biological tissues and other complex systems. This LPP exhibits a high luminescent intensity and a long emission duration in the NIR region (700-800 nm). The applicability of this phosphor to tissue imaging is demonstrated experimentally. Its persistent luminescence (PersL) can easily penetrate approximately 2 mm of pork flesh. More importantly, this phosphor can be re-charged in situ using a red LED or laser diode array to provide renewed NIR PersL for biological tissues, which is beneficial for long-term biological tissue imaging applications with high signal-to-noise ratios. Systematic investigations of the nature of energy traps and PersL mechanisms are also reported in this paper.


Assuntos
Corantes Fluorescentes/química , Medições Luminescentes/métodos , Carne/análise , Animais , Transferência Ressonante de Energia de Fluorescência , Gálio/química , Germânio/química , Luz , Lítio/química , Suínos , Titânio/química , Raios Ultravioleta , Zinco/química
20.
ACS Appl Mater Interfaces ; 11(38): 35023-35029, 2019 Sep 25.
Artigo em Inglês | MEDLINE | ID: mdl-31474109

RESUMO

In the current "big data" era, the state-of-the-art optical data storage (ODS) has become a front-runner in the competing data storage technologies. As one of the most promising methods for breaking the physical limitation suffered by traditional ones, the advance of optically stimulated luminescence (OSL) based optical storage technique is now still limited by the simultaneous single-level write-in and readout in a same spot. In this work, to bridge the data-capacity gap, we report for the first time a novel and promising nonphysical multidimensional OSL-based ODS flexible medium for erasable multilevel optical data recording and reading. We tailor multidimensional traps with discrete, narrowly distributed energy levels through (multi-)codoping of selective trivalent rare-earth ions into Eu2+-activated barium orthosilicate (Ba2SiO4). Upon UV/blue light illumination, information can be sequentially recorded in different traps assisted by thermal cleaning with an increase of storage capacity by orders of magnitude, which is addressable individually in the whole domain or bit-by-bit mode without the crosstalk by designed thermal/optical stimuli. Remarkably, good data retention and robust fatigue resistance have been achieved in recycle data recording. Insight is forged from charge carrier dynamics and interactions with traps for a universal method of data storage, and proof-of-concept applications are also demonstrated, thereby providing the way to not only rewritable multilevel ODS but also high-security encryption/decryption.

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