Detalhe da pesquisa
1.
Clinical tests of neurotrophic factors for human neurodegenerative diseases, part 2: Where do we stand and where must we go next?
Neurobiol Dis
; 97(Pt B): 169-178, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27063797
2.
Clinical tests of neurotrophic factors for human neurodegenerative diseases, part 1: Where have we been and what have we learned?
Neurobiol Dis
; 97(Pt B): 156-168, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27063798
3.
Dopamine-dependent compensation maintains motor behavior in mice with developmental ablation of dopaminergic neurons.
J Neurosci
; 33(43): 17095-107, 2013 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-24155314
4.
Enhanced neurotrophic distribution, cell signaling and neuroprotection following substantia nigral versus striatal delivery of AAV2-NRTN (CERE-120).
Neurobiol Dis
; 58: 38-48, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23631873
5.
RET signaling is required for survival and normal function of nonpeptidergic nociceptors.
J Neurosci
; 30(11): 3983-94, 2010 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20237269
6.
Properly scaled and targeted AAV2-NRTN (neurturin) to the substantia nigra is safe, effective and causes no weight loss: support for nigral targeting in Parkinson's disease.
Neurobiol Dis
; 44(1): 38-52, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21704161
7.
Bioactivity of AAV2-neurturin gene therapy (CERE-120): differences between Parkinson's disease and nonhuman primate brains.
Mov Disord
; 26(1): 27-36, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21322017
8.
The limited role of NH2-terminal c-Jun phosphorylation in neuronal apoptosis: identification of the nuclear pore complex as a potential target of the JNK pathway.
J Cell Biol
; 170(3): 401-11, 2005 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16061693
9.
Neurturin-mediated ret activation is required for retinal function.
J Neurosci
; 28(16): 4123-35, 2008 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-18417692
10.
Cyclosporin A inhibits caspase-independent death of NGF-deprived sympathetic neurons: a potential role for mitochondrial permeability transition.
J Cell Biol
; 157(5): 771-81, 2002 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-12021257
11.
Alternating metabolic pathways in NGF-deprived sympathetic neurons affect caspase-independent death.
J Cell Biol
; 162(2): 245-56, 2003 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-12876275
12.
Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice.
J Cell Biol
; 157(3): 441-53, 2002 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-11980919
13.
NGF utilizes c-Ret via a novel GFL-independent, inter-RTK signaling mechanism to maintain the trophic status of mature sympathetic neurons.
Neuron
; 33(2): 261-73, 2002 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-11804573
14.
GFRalpha1 expression in cells lacking RET is dispensable for organogenesis and nerve regeneration.
Neuron
; 44(4): 623-36, 2004 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-15541311
15.
JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis.
Neuron
; 38(6): 899-914, 2003 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-12818176
16.
Glial cell line-derived neurotrophic factor-dependent recruitment of Ret into lipid rafts enhances signaling by partitioning Ret from proteasome-dependent degradation.
J Neurosci
; 26(10): 2777-87, 2006 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-16525057
17.
RET is dispensable for maintenance of midbrain dopaminergic neurons in adult mice.
J Neurosci
; 26(43): 11230-8, 2006 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-17065462
18.
Lipid rafts in neuronal signaling and function.
Trends Neurosci
; 25(8): 412-7, 2002 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12127758
19.
Exogenous smac induces competence and permits caspase activation in sympathetic neurons.
J Neurosci
; 22(18): 8018-27, 2002 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12223555
20.
Glial cell line-derived neurotrophic factor promotes the survival of early postnatal spinal motor neurons in the lateral and medial motor columns in slice culture.
J Neurosci
; 22(10): 3953-62, 2002 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12019314