Detalhe da pesquisa
1.
Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation.
Mol Cell
; 67(4): 566-578.e10, 2017 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28803781
2.
A phase 2 study of neoadjuvant chemotherapy plus durvalumab in resectable locally advanced head and neck squamous cell carcinoma.
Cancer
; 129(21): 3381-3389, 2023 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37395170
3.
Allosteric differences dictate GroEL complementation of E. coli.
FASEB J
; 36(3): e22198, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35199390
4.
Bis-aryl-α,ß-unsaturated ketone (ABK) chaperonin inhibitors exhibit selective cytotoxicity to colorectal cancer cells that correlates with levels of aberrant HSP60 in the cytosol.
Bioorg Med Chem
; 75: 117072, 2022 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36356534
5.
RNA Expression Profiling of Lymphoepithelioma-Like Carcinoma of the Bladder Reveals a Basal-Like Molecular Subtype.
Am J Pathol
; 190(1): 134-144, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31610173
6.
Genomic characteristics and prognostic significance of co-mutated ASXL1/SRSF2 acute myeloid leukemia.
Am J Hematol
; 96(4): 462-470, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33502020
7.
Exploiting the HSP60/10 chaperonin system as a chemotherapeutic target for colorectal cancer.
Bioorg Med Chem
; 40: 116129, 2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33971488
8.
Autoimmune Cytopenia as an Early and Initial Presenting Manifestation in Activated PI3 Kinase Delta Syndrome: Case Report and Review.
J Pediatr Hematol Oncol
; 43(8): 281-287, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34054047
9.
Parkinson's disease-associated mutations in the GTPase domain of LRRK2 impair its nucleotide-dependent conformational dynamics.
J Biol Chem
; 294(15): 5907-5913, 2019 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30796162
10.
Analogs of nitrofuran antibiotics are potent GroEL/ES inhibitor pro-drugs.
Bioorg Med Chem
; 28(22): 115710, 2020 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33007545
11.
Exposome and Immunity Training: How Pathogen Exposure Order Influences Innate Immune Cell Lineage Commitment and Function.
Int J Mol Sci
; 21(22)2020 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33187101
12.
HSP60/10 chaperonin systems are inhibited by a variety of approved drugs, natural products, and known bioactive molecules.
Bioorg Med Chem Lett
; 29(9): 1106-1112, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30852084
13.
A high throughput substrate binding assay reveals hexachlorophene as an inhibitor of the ER-resident HSP70 chaperone GRP78.
Bioorg Med Chem Lett
; 29(14): 1689-1693, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31129054
14.
Dual-targeting GroEL/ES chaperonin and protein tyrosine phosphatase B (PtpB) inhibitors: A polypharmacology strategy for treating Mycobacterium tuberculosis infections.
Bioorg Med Chem Lett
; 29(13): 1665-1672, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31047750
15.
Semi-quantitative models for identifying potent and selective transthyretin amyloidogenesis inhibitors.
Bioorg Med Chem Lett
; 27(15): 3441-3449, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28625364
16.
Determinants of nucleosome organization in primary human cells.
Nature
; 474(7352): 516-20, 2011 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21602827
17.
Large Cell Change in a Small Liver: A Histological Clue to Short Telomere Syndromes?
Hepatology
; 72(6): 2231-2234, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32294263
18.
Targeting the HSP60/10 chaperonin systems of Trypanosoma brucei as a strategy for treating African sleeping sickness.
Bioorg Med Chem Lett
; 26(21): 5247-5253, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27720295
19.
GroEL/ES inhibitors as potential antibiotics.
Bioorg Med Chem Lett
; 26(13): 3127-3134, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27184767
20.
A phase IV, single-center, crossover evaluation of the efficacy of an external nasal dilator strip in children with nasal congestion.
Allergy Asthma Proc
; 37(3): 242-7, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27178892