Assuntos
Glucocorticoides/uso terapêutico , Lúpus Eritematoso Sistêmico/complicações , Linfadenopatia/etiologia , Síndrome de Ativação Macrofágica/patologia , Adulto , Exame de Medula Óssea , Feminino , Febre/etiologia , Testes Hematológicos , Humanos , Síndrome de Ativação Macrofágica/diagnóstico , Síndrome de Ativação Macrofágica/tratamento farmacológico , Síndrome de Ativação Macrofágica/etiologiaRESUMO
INTRODUCTION: We examined the association between admission body mass index (BMI) and discharge rehabilitation functional outcome using the Functional Independence Measure (FIM) in an East-Asian cohort of stroke patients during inpatient rehabilitation. METHODS: A prospective observational cohort study of stroke patients admitted to a single inpatient rehabilitation unit was conducted. Using the World Health Organisation Asian standards, BMI was classified as underweight (< 18.5 kg/m2), normal (18.5-22.9 kg/m2) and overweight (≥ 23 kg/m2). The primary outcome measure was discharge FIM, and secondary outcomes included FIM gain, FIM efficiency and FIM effectiveness. RESULTS: 247 stroke subjects were enrolled (mean age 59.48 [SD 12.35] years, 64.4% [159] male, 52.6% [130] ischaemic stroke). The distributions of underweight, normal and overweight BMI were 10.9% (27), 33.2% (82), and 55.9% (138) respectively on admission and 11.7% (29), 38.1% (94), and 50.2% (124) respectively on discharge. Significant small decreases in BMI from admission (median [IQR]: 23.58 [23.40, 24.70]) to discharge (median [IQR]: 23.12 [22.99, 24.21]) (p < 0.001) were found. Similarly, clinically significant FIM gains (mean ïFIM 26.71 [95% CI: 24.73, 28.69], p < 0.001) were noted after 36 days of median length of stay. No significant relationships were found between BMI and discharge FIM (p = 0.600), FIM gain (p = 0.254), FIM efficiency (p = 0.412) nor FIM effectiveness (p = 0.796). CONCLUSION: Findings from this study unequivocally support the benefits of acute inpatient stroke rehabilitation. Patients in the obese BMI range tended to normalise during rehabilitation. BMI, whether underweight, normal, or overweight was not correlated with discharge FIM.
RESUMO
INTRODUCTION: Anxiety among house officers may impair functioning and health care delivery. This study aimed to determine the association between anxiety among house officers at Universiti Kebangsaan Malaysia Medical Center, sociodemographic and work-related factors. METHODS: A cross-sectional study using the self-rated and validated Malay Depressive Anxiety and Stress Scale 21, the General Stressor Questionnaire and a sociodemographic questionnaire. RESULTS: Of the 89 house officers, 60.7% were anxious. Multivariate logistic analysis showed work-related challenges, performance pressure (odds ratio [OR] = 9.000, 95% confidence interval [CI] = 1.812-44.705), poor relationship with supervisors (OR = 5.212, 95% CI = 2.033-3.365), poor relationship with colleagues (OR = 4.642, 95% CI = 1.816-11.866), bureaucratic constraints (OR = 3.810, 95% CI = 1.541-9.415) and poor job prospects (OR = 3.745, 95% CI = 1.505-9.321) strongly associated with anxiety. Family-related stressors were less significant (OR = 1.800, 95% CI = 0.760-4.266) unless they were work related (work-family conflicts [OR = 8.253, 95% CI = 2.652-25.684]). DISCUSSION: Almost two-thirds of this cohort reported work-related anxiety symptoms. Administrators need to address these mental health needs early. The subsequent improvement in communication skills, conflict resolution and anxiety reduction will result in short- and long-term benefits towards the young doctors's mental health. The cascading impact on these individuals, thus empowered, will be good work-life balance, improved patient care and safety, a satisfying medical career whilst contributing maximally to the country's health care.