Detalhe da pesquisa
1.
The VEGFR/PDGFR tyrosine kinase inhibitor, ABT-869, blocks necroptosis by targeting RIPK1 kinase.
Biochem J
; 480(9): 665-684, 2023 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37115711
2.
Exploration of the P3 region of PEXEL peptidomimetics leads to a potent inhibitor of the Plasmodium protease, plasmepsin V.
Bioorg Med Chem
; 24(9): 1993-2010, 2016 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27021426
3.
Discovery of Acylsulfonohydrazide-Derived Inhibitors of the Lysine Acetyltransferase, KAT6A, as Potent Senescence-Inducing Anti-Cancer Agents.
J Med Chem
; 63(9): 4655-4684, 2020 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32118427
4.
Identification of 5-Substituted 2-Acylaminothiazoles That Activate Tat-Mediated Transcription in HIV-1 Latency Models.
J Med Chem
; 62(10): 5148-5175, 2019 05 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30973727
5.
Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3.
Cell Rep
; 28(13): 3309-3319.e5, 2019 09 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-31553902
6.
Enhanced antimalarial activity of plasmepsin V inhibitors by modification of the P2 position of PEXEL peptidomimetics.
Eur J Med Chem
; 154: 182-198, 2018 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29800827