Detalhe da pesquisa
1.
Organoid Modeling of the Tumor Immune Microenvironment.
Cell
; 175(7): 1972-1988.e16, 2018 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30550791
2.
Progenitor identification and SARS-CoV-2 infection in human distal lung organoids.
Nature
; 588(7839): 670-675, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33238290
3.
Deficient Activity of the Nuclease MRE11A Induces T Cell Aging and Promotes Arthritogenic Effector Functions in Patients with Rheumatoid Arthritis.
Immunity
; 45(4): 903-916, 2016 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27742546
4.
Age-Associated Failure To Adjust Type I IFN Receptor Signaling Thresholds after T Cell Activation.
J Immunol
; 195(3): 865-74, 2015 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26091718
5.
DNA-dependent protein kinase inhibition blocks asthma in mice and modulates human endothelial and CD4⺠T-cell function without causing severe combined immunodeficiency.
J Allergy Clin Immunol
; 135(2): 425-40, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25441643
6.
Apoptotic DNA fragmentation may be a cooperative activity between caspase-activated deoxyribonuclease and the poly(ADP-ribose) polymerase-regulated DNAS1L3, an endoplasmic reticulum-localized endonuclease that translocates to the nucleus during apoptosis.
J Biol Chem
; 288(5): 3460-8, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23229555
7.
Minocycline blocks asthma-associated inflammation in part by interfering with the T cell receptor-nuclear factor κB-GATA-3-IL-4 axis without a prominent effect on poly(ADP-ribose) polymerase.
J Biol Chem
; 288(3): 1458-68, 2013 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23184953
8.
Unconventional activation of PRKDC by TNF-α: deciphering its crucial role in Th1-mediated inflammation beyond DNA repair as part of the DNA-PK complex.
J Inflamm (Lond)
; 21(1): 14, 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38689261
9.
PDZK1 is a novel factor in breast cancer that is indirectly regulated by estrogen through IGF-1R and promotes estrogen-mediated growth.
Mol Med
; 19: 253-62, 2013 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23821363
10.
Poly(ADP-ribose) polymerase-1 is a determining factor in Crm1-mediated nuclear export and retention of p65 NF-kappa B upon TLR4 stimulation.
J Immunol
; 185(3): 1894-902, 2010 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20610652
11.
Requirement for inducible nitric oxide synthase in chronic allergen exposure-induced pulmonary fibrosis but not inflammation.
J Immunol
; 185(5): 3076-85, 2010 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20668217
12.
Phosphorylation of p50 NF-kappaB at a single serine residue by DNA-dependent protein kinase is critical for VCAM-1 expression upon TNF treatment.
J Biol Chem
; 285(52): 41152-60, 2010 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20966071
13.
Cordycepin blocks lung injury-associated inflammation and promotes BRCA1-deficient breast cancer cell killing by effectively inhibiting PARP.
Mol Med
; 17(9-10): 893-900, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21607289
14.
Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures.
bioRxiv
; 2020 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32743583
15.
High-fat diet induces lung remodeling in ApoE-deficient mice: an association with an increase in circulatory and lung inflammatory factors.
Lab Invest
; 89(11): 1243-51, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19752857
16.
Complete Remission of Widely Metastatic Human Epidermal Growth Factor Receptor 2-Amplified Pancreatic Adenocarcinoma After Precision Immune and Targeted Therapy With Description of Sequencing and Organoid Correlates.
JCO Precis Oncol
; 7: e2100489, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37079860
17.
NADPH oxidase deficiency underlies dysfunction of aged CD8+ Tregs.
J Clin Invest
; 126(5): 1953-67, 2016 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27088800
18.
ICAD deficiency in human colon cancer and predisposition to colon tumorigenesis: linkage to apoptosis resistance and genomic instability.
PLoS One
; 8(2): e57871, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23451280
19.
Downregulation of NFAT5 by RNA interference reduces monoclonal antibody productivity of hybridoma cells.
Cell Res
; 17(3): 264-70, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17310218
20.
Pretreatment with insulin enhances anticancer functions of 5-fluorouracil in human esophageal and colonic cancer cells.
Acta Pharmacol Sin
; 28(5): 721-30, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17439729