Detalhe da pesquisa
1.
PET Imaging in Preclinical Anti-Aß Drug Development.
Pharm Res
; 39(7): 1481-1496, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35501533
2.
Prolyl Oligopeptidase Regulates Dopamine Transporter Oligomerization and Phosphorylation in a PKC- and ERK-Independent Manner.
Int J Mol Sci
; 22(4)2021 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33579026
3.
Prolyl oligopeptidase inhibition activates autophagy via protein phosphatase 2A.
Pharmacol Res
; 151: 104558, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31759088
4.
Inhibition of Prolyl Oligopeptidase Restores Spontaneous Motor Behavior in the α-Synuclein Virus Vector-Based Parkinson's Disease Mouse Model by Decreasing α-Synuclein Oligomeric Species in Mouse Brain.
J Neurosci
; 36(49): 12485-12497, 2016 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27927963
5.
Long-term effects of immunotherapy with a brain penetrating Aß antibody in a mouse model of Alzheimer's disease.
Alzheimers Res Ther
; 15(1): 90, 2023 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37131196
6.
Nonpeptidic Oxazole-Based Prolyl Oligopeptidase Ligands with Disease-Modifying Effects on α-Synuclein Mouse Models of Parkinson's Disease.
J Med Chem
; 66(11): 7475-7496, 2023 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37248563
7.
A prolyl oligopeptidase inhibitor reduces tau pathology in cellular models and in mice with tauopathy.
Sci Transl Med
; 15(691): eabq2915, 2023 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37043557
8.
Brain pharmacokinetics of mono- and bispecific amyloid-ß antibodies in wild-type and Alzheimer's disease mice measured by high cut-off microdialysis.
Fluids Barriers CNS
; 19(1): 99, 2022 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36510227
9.
Reduction of αSYN Pathology in a Mouse Model of PD Using a Brain-Penetrating Bispecific Antibody.
Pharmaceutics
; 14(7)2022 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35890306
10.
Removal of proteinase K resistant αSyn species does not correlate with cell survival in a virus vector-based Parkinson's disease mouse model.
Neuropharmacology
; 218: 109213, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35964686
11.
Multiplexed analysis of amino acids in mice brain microdialysis samples using isobaric labeling and liquid chromatography-high resolution tandem mass spectrometry.
J Chromatogr A
; 1656: 462537, 2021 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34537659
12.
Behavioural and dopaminergic changes in double mutated human A30P*A53T alpha-synuclein transgenic mouse model of Parkinson´s disease.
Sci Rep
; 9(1): 17382, 2019 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31758049
13.
New tricks of prolyl oligopeptidase inhibitors - A common drug therapy for several neurodegenerative diseases.
Biochem Pharmacol
; 161: 113-120, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30660495
14.
Removal of prolyl oligopeptidase reduces alpha-synuclein toxicity in cells and in vivo.
Sci Rep
; 8(1): 1552, 2018 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-29367610
15.
Prolyl Oligopeptidase Regulates Dopamine Transporter Phosphorylation in the Nigrostriatal Pathway of Mouse.
Mol Neurobiol
; 55(1): 470-482, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27966077
16.
Combination of CDNF and Deep Brain Stimulation Decreases Neurological Deficits in Late-stage Model Parkinson's Disease.
Neuroscience
; 374: 250-263, 2018 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29408408