Detalhe da pesquisa
1.
Synthesis of 4ß-carbamoyl epipodophyllotoxins as potential antitumour agents.
Bioorg Med Chem
; 19(9): 2975-9, 2011 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21489802
2.
Synthesis, anticancer activity and apoptosis inducing ability of anthranilamide-PBD conjugates.
Bioorg Med Chem Lett
; 20(11): 3310-3, 2010 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20444601
3.
Synthesis, anticancer activity and mitochondrial mediated apoptosis inducing ability of 2,5-diaryloxadiazole-pyrrolobenzodiazepine conjugates.
Bioorg Med Chem
; 18(18): 6666-77, 2010 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20732817
4.
Synthesis, DNA-binding ability and anticancer activity of benzothiazole/benzoxazole-pyrrolo[2,1-c][1,4]benzodiazepine conjugates.
Bioorg Med Chem
; 18(13): 4747-61, 2010 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20627593
5.
Quinazolinone linked pyrrolo[2,1-c][1,4]benzodiazepine (PBD) conjugates: Design, synthesis and biological evaluation as potential anticancer agents.
Bioorg Med Chem
; 18(2): 526-42, 2010 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20031423
6.
Synthesis of 1,2,3-triazole-linked pyrrolobenzodiazepine conjugates employing 'click' chemistry: DNA-binding affinity and anticancer activity.
Bioorg Med Chem Lett
; 18(4): 1468-73, 2008 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18207392
7.
Remarkable DNA binding affinity and potential anticancer activity of pyrrolo[2,1-c][1,4]benzodiazepine-naphthalimide conjugates linked through piperazine side-armed alkane spacers.
Bioorg Med Chem
; 16(15): 7218-24, 2008 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18656370
8.
Phosphonate-linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates: synthesis, DNA-binding affinity and cytotoxicity.
Bioorg Med Chem
; 16(7): 3895-906, 2008 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18262426
9.
Synthesis, DNA-binding ability and evaluation of antitumour activity of triazolo[1,2,4]benzothiadiazine linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates.
Bioorg Med Chem
; 16(16): 7804-10, 2008 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18657979
10.
Design, synthesis and biological evaluation of novel pyrazolochalcones as potential modulators of PI3K/Akt/mTOR pathway and inducers of apoptosis in breast cancer cells.
Eur J Med Chem
; 139: 305-324, 2017 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28803046
11.
Decreased B16F10 melanoma growth and impaired tumour vascularization in BDF1 mice with quercetin-cyclodextrin binary system.
J Pharm Pharmacol
; 58(10): 1351-8, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17034658
12.
Remarkable anti-breast cancer activity of ferrocene tagged multi-functionalized 1,4-dihydropyrimidines.
Eur J Med Chem
; 65: 232-9, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23711834
13.
Design and synthesis of (S)- and (R)-enantiomers of [4-(2-hydroxy-1-phenylethylimino)pent-2-ol]dimethyltin(iv) and 2,2-dimethyl-4-phenyl-1,3,2-oxazastannolidine: in vitro antitumor activity against human tumor cell lines and in vivo assay of (S)-enantiomers.
Dalton Trans
; 42(10): 3390-401, 2013 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23250651
14.
Carbohydrate-conjugate heterobimetallic complexes: synthesis, DNA binding studies, artificial nuclease activity and in vitro cytotoxicity.
Carbohydr Res
; 346(18): 2886-95, 2011 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22055812
15.
Synthesis of aryl-substituted naphthalene-linked pyrrolobenzodiazepine conjugates as potential anticancer agents with apoptosis-inducing ability.
ChemMedChem
; 6(9): 1665-79, 2011 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-21732540
16.
Design, Synthesis and Evaluation of Novel 1-(Substituted Acetyl)-4-(10-Bromo-8-Chloro-5,6-Dihydro-11H-Benzo[5,6]Cyclohepta[1,2-B]Pyridine-11-Ylidene)piperidines as Antitumor Agents and Farnesyl Protein Transferase Inhibitors.
Indian J Pharm Sci
; 72(5): 663-7, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21695007
17.
Synthesis of carbohydrate-conjugate heterobimetallic Cu(II)-Sn(2)(IV) and Zn(II)-Sn(2)(IV) complexes; their interactions with CT DNA and nucleotides; DNA cleavage, in-vitro cytotoxicity.
Eur J Med Chem
; 45(11): 4797-806, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20813437
18.
Design, synthesis and biological evaluation of 3,5-diaryl-isoxazoline/isoxazole-pyrrolobenzodiazepine conjugates as potential anticancer agents.
Eur J Med Chem
; 45(9): 3924-37, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20557981
19.
Molecular encapsulation of thalidomide with sulfobutyl ether-7 beta-cyclodextrin for immediate release property: enhanced in vivo antitumor and antiangiogenesis efficacy in mice.
Drug Dev Ind Pharm
; 34(2): 149-56, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18302033
20.
Synthesis and evaluation of novel N-substituted-6-methoxynaphthalene-2-carboxamides as potential chemosensitizing agents for cancer.
Chem Pharm Bull (Tokyo)
; 56(7): 894-6, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18591797