Detalhe da pesquisa
1.
Novel 4-[4-(4-methylpiperazin-1-yl)phenyl]-6-arylpyrimidine derivatives and their antitrypanosomal activities against T.brucei.
Bioorg Med Chem Lett
; 109: 129825, 2024 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38823730
2.
Antiprotozoal Activity of Plants Used in the Management of Sleeping Sickness in Angola and Bioactivity-Guided Fractionation of Brasenia schreberi J.F.Gmel and Nymphaea lotus L. Active against T. b. rhodesiense.
Molecules
; 29(7)2024 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38611890
3.
An Alba-domain protein required for proteome remodelling during trypanosome differentiation and host transition.
PLoS Pathog
; 17(1): e1009239, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33493187
4.
Jozibrevine D from Ancistrocladus ileboensis, the fifth alkaloid in a series of six possible atropo-diastereomeric naphthylisoquinoline dimers, showing antiparasitic and antileukemic activities.
Bioorg Med Chem Lett
; 86: 129258, 2023 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36972793
5.
Structure-Activity Relationships and Antiplasmodial Potencies of Novel 3,4-Disubstituted 1,2,5-Oxadiazoles.
Int J Mol Sci
; 24(19)2023 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37833929
6.
Generation of Aurachin Derivatives by Whole-Cell Biotransformation and Evaluation of Their Antiprotozoal Properties.
Molecules
; 28(3)2023 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36770729
7.
Key Contributions by the Swiss Tropical and Public Health Institute Towards New and Better Drugs for Tropical Diseases.
Chimia (Aarau)
; 77(9): 593-602, 2023 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38047835
8.
Antischistosomal tetrahydro-γ-carboline sulfonamides.
Bioorg Med Chem Lett
; 59: 128546, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35031451
9.
Discovery of Ircinianin Lactones B and C-Two New Cyclic Sesterterpenes from the Marine Sponge Ircinia wistarii.
Mar Drugs
; 20(8)2022 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-36005535
10.
2-(Nitroaryl)-5-Substituted-1,3,4-Thiadiazole Derivatives with Antiprotozoal Activities: In Vitro and In Vivo Study.
Molecules
; 27(17)2022 Aug 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36080325
11.
Efficient Oxidative Dearomatisations of Substituted Phenols Using Hypervalent Iodine (III) Reagents and Antiprotozoal Evaluation of the Resulting Cyclohexadienones against T. b. rhodesiense and P. falciparum Strain NF54.
Molecules
; 27(19)2022 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36235096
12.
Synthesis and Antiprotozoal Activity of Azabicyclo-Nonane Pyrimidine Hybrids.
Molecules
; 28(1)2022 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36615504
13.
Isolation and Structural Elucidation of Compounds from Pleiocarpa bicarpellata and Their In Vitro Antiprotozoal Activity.
Molecules
; 27(7)2022 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35408605
14.
Antiprotozoal Activity of Azabicyclo-Nonanes Linked to Tetrazole or Sulfonamide Cores.
Molecules
; 27(19)2022 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36234752
15.
A Modular Approach to the Antifungal Sphingofungin Family: Concise Total Synthesis of Sphingofunginâ A andâ C.
Angew Chem Int Ed Engl
; 61(5): e202112616, 2022 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34677894
16.
Leveraging Electron-Deficient Iminium Intermediates in a General Synthesis of Valuable Amines.
Angew Chem Int Ed Engl
; 61(20): e202115435, 2022 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35103377
17.
Activation, Structure, Biosynthesis and Bioactivity of Glidobactin-like Proteasome Inhibitors from Photorhabdus laumondii.
Chembiochem
; 22(9): 1582-1588, 2021 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33452852
18.
Quest for a potent antimalarial drug lead: Synthesis and evaluation of 6,7-dimethoxyquinazoline-2,4-diamines.
Bioorg Med Chem
; 33: 116018, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33524940
19.
Spirombandakamine A3 and Cyclombandakamines A8 and A9, Polycyclic Naphthylisoquinoline Dimers, with Antiprotozoal Activity, from a Congolese Ancistrocladus Plant.
J Nat Prod
; 84(4): 1335-1344, 2021 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33843232
20.
The Alkaloid-Enriched Fraction of Pachysandra terminalis (Buxaceae) Shows Prominent Activity against Trypanosoma brucei rhodesiense.
Molecules
; 26(3)2021 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33498621