Detalhe da pesquisa
1.
Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches.
Cell
; 185(2): 379-396.e38, 2022 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35021063
2.
Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates.
Nature
; 615(7953): 678-686, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36922586
3.
A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction.
Nature
; 598(7881): 504-509, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34616043
4.
A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate.
Nature
; 590(7845): 320-325, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33260195
5.
Animal models for COVID-19.
Nature
; 586(7830): 509-515, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32967005
6.
A SCID Mouse Model To Evaluate the Efficacy of Antivirals against SARS-CoV-2 Infection.
J Virol
; 96(16): e0075822, 2022 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35924921
7.
Favipiravir at high doses has potent antiviral activity in SARS-CoV-2-infected hamsters, whereas hydroxychloroquine lacks activity.
Proc Natl Acad Sci U S A
; 117(43): 26955-26965, 2020 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33037151
8.
Publisher Correction: A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction.
Nature
; 599(7883): E2, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34671169
9.
A Viral Polymerase Inhibitor Reduces Zika Virus Replication in the Reproductive Organs of Male Mice.
Int J Mol Sci
; 20(9)2019 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31032814
10.
Multiplexed multicolor antiviral assay amenable for high-throughput research.
Nat Commun
; 15(1): 42, 2024 Jan 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38168091
11.
Discovery of JNJ-1802, a First-in-Class Pan-Serotype Dengue Virus NS4B Inhibitor.
J Med Chem
; 67(5): 4063-4082, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38482827
12.
Establishment of a robust rat hepatitis E virus fecal-oral infection model and validation for antiviral studies.
Antiviral Res
; 216: 105670, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37451630
13.
Discovery of Acyl-Indole Derivatives as Pan-Serotype Dengue Virus NS4B Inhibitors.
J Med Chem
; 66(13): 8808-8821, 2023 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37389813
14.
Expanded profiling of Remdesivir as a broad-spectrum antiviral and low potential for interaction with other medications in vitro.
Sci Rep
; 13(1): 3131, 2023 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36823196
15.
HIV protease inhibitors Nelfinavir and Lopinavir/Ritonavir markedly improve lung pathology in SARS-CoV-2-infected Syrian hamsters despite lack of an antiviral effect.
Antiviral Res
; 202: 105311, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35390430
16.
Comparing infectivity and virulence of emerging SARS-CoV-2 variants in Syrian hamsters.
EBioMedicine
; 68: 103403, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-34049240
17.
The combined treatment of Molnupiravir and Favipiravir results in a potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model.
EBioMedicine
; 72: 103595, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34571361
18.
Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains.
Nat Commun
; 12(1): 916, 2021 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33568638
19.
An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models.
Sci Transl Med
; 13(621): eabi7826, 2021 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34609205
20.
Itraconazole for COVID-19: preclinical studies and a proof-of-concept randomized clinical trial.
EBioMedicine
; 66: 103288, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33752127