Detalhe da pesquisa
1.
A digoxin derivative that potently reduces intraocular pressure: efficacy and mechanism of action in different animal models.
Am J Physiol Cell Physiol
; 326(5): C1505-C1519, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38557355
2.
A missense mutation converts the Na+,K+-ATPase into an ion channel and causes therapy-resistant epilepsy.
J Biol Chem
; 297(6): 101355, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34717959
3.
Specific phospholipid binding to Na,K-ATPase at two distinct sites.
Proc Natl Acad Sci U S A
; 114(11): 2904-2909, 2017 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28242691
4.
Digoxin derivatives with selectivity for the α2ß3 isoform of Na,K-ATPase potently reduce intraocular pressure.
Proc Natl Acad Sci U S A
; 112(44): 13723-8, 2015 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26483500
5.
Do Src Kinase and Caveolin Interact Directly with Na,K-ATPase?
J Biol Chem
; 291(22): 11736-50, 2016 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27022017
6.
Selective Assembly of Na,K-ATPase α2ß2 Heterodimers in the Heart: DISTINCT FUNCTIONAL PROPERTIES AND ISOFORM-SELECTIVE INHIBITORS.
J Biol Chem
; 291(44): 23159-23174, 2016 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27624940
7.
Familial hyperkalemia and hypertension and a hypothesis to explain proximal renal tubular acidosis.
Proc Natl Acad Sci U S A
; 116(33): 16173-16174, 2019 08 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31371517
8.
Stimulation, inhibition, or stabilization of Na,K-ATPase caused by specific lipid interactions at distinct sites.
J Biol Chem
; 290(8): 4829-4842, 2015 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25533463
9.
Molecular Mechanisms and Kinetic Effects of FXYD1 and Phosphomimetic Mutants on Purified Human Na,K-ATPase.
J Biol Chem
; 290(48): 28746-59, 2015 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-26429909
10.
Cardiac glycosides induced toxicity in human cells expressing α1-, α2-, or α3-isoforms of Na-K-ATPase.
Am J Physiol Cell Physiol
; 309(2): C126-35, 2015 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25994790
11.
Ouabain-induced internalization and lysosomal degradation of the Na+/K+-ATPase.
J Biol Chem
; 289(2): 1049-59, 2014 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24275648
12.
Digoxin derivatives with enhanced selectivity for the α2 isoform of Na,K-ATPase: effects on intraocular pressure in rabbits.
J Biol Chem
; 289(30): 21153-62, 2014 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24917667
13.
Neutral phospholipids stimulate Na,K-ATPase activity: a specific lipid-protein interaction.
J Biol Chem
; 288(14): 10073-10081, 2013 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23430748
14.
Association of Familial Hyperkalemia and Hypertension with Proximal Renal Tubular Acidosis and Epileptic Seizures.
Nephron
; 148(3): 179-184, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-37666233
15.
Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na+/K+-ATPase.
Mol Cancer
; 12: 33, 2013 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23621895
16.
Surface charges of the membrane crucially affect regulation of Na,K-ATPase by phospholemman (FXYD1).
J Membr Biol
; 246(12): 967-79, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24105627
17.
FXYD proteins stabilize Na,K-ATPase: amplification of specific phosphatidylserine-protein interactions.
J Biol Chem
; 286(11): 9699-712, 2011 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21228272
18.
Stabilization of the α2 isoform of Na,K-ATPase by mutations in a phospholipid binding pocket.
J Biol Chem
; 286(50): 42888-99, 2011 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-22027833
19.
Phospholemman (FXYD1) raises the affinity of the human α1ß1 isoform of Na,K-ATPase for Na ions.
Biochemistry
; 50(18): 3736-48, 2011 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-21449573
20.
Selectivity of digitalis glycosides for isoforms of human Na,K-ATPase.
J Biol Chem
; 285(25): 19582-92, 2010 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20388710