Detalhe da pesquisa
1.
Microglial NMDA receptors drive pro-inflammatory responses via PARP-1/TRMP2 signaling.
Glia
; 68(7): 1421-1434, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32036619
2.
Exposure to gestational diabetes mellitus induces neuroinflammation, derangement of hippocampal neurons, and cognitive changes in rat offspring.
J Neuroinflammation
; 14(1): 80, 2017 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28388927
3.
NF-κB transcriptional activation by TNFα requires phospholipase C, extracellular signal-regulated kinase 2 and poly(ADP-ribose) polymerase-1.
J Neuroinflammation
; 12: 229, 2015 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26637332
4.
Inhibition of NADPH oxidase activation reduces EAE-induced white matter damage in mice.
J Neuroinflammation
; 12: 104, 2015 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26017142
5.
Poly(ADP-ribose) polymerase-1-induced NAD(+) depletion promotes nuclear factor-κB transcriptional activity by preventing p65 de-acetylation.
Biochim Biophys Acta
; 1833(8): 1985-91, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23597856
6.
Cortical astrocyte N-methyl-D-aspartate receptors influence whisker barrel activity and sensory discrimination in mice.
Nat Commun
; 15(1): 1571, 2024 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38383567
7.
Poly(ADP-ribose) polymerase 2 contributes to neuroinflammation and neurological dysfunction in mouse experimental autoimmune encephalomyelitis.
J Neuroinflammation
; 10: 49, 2013 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23607899
8.
CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease.
J Biol Chem
; 286(37): 32713-22, 2011 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21771791
9.
Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor.
J Neuroinflammation
; 9: 31, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22335939
10.
Recurrent/moderate hypoglycemia induces hippocampal dendritic injury, microglial activation, and cognitive impairment in diabetic rats.
J Neuroinflammation
; 9: 182, 2012 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-22830525
11.
Prevention of hypoglycemia-induced neuronal death by minocycline.
J Neuroinflammation
; 9: 225, 2012 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22998689
12.
N-acetylcysteine prevents loss of dopaminergic neurons in the EAAC1-/- mouse.
Ann Neurol
; 69(3): 509-20, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21446024
13.
NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death.
J Neurosci
; 30(8): 2967-78, 2010 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20181594
14.
EAAC1 gene deletion alters zinc homeostasis and exacerbates neuronal injury after transient cerebral ischemia.
J Neurosci
; 30(46): 15409-18, 2010 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-21084597
15.
Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid ß.
J Neuroinflammation
; 8: 152, 2011 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22051244
16.
PARP-DNA trapping ability of PARP inhibitors jeopardizes astrocyte viability: Implications for CNS disease therapeutics.
Neuropharmacology
; 187: 108502, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33631119
17.
Zinc triggers microglial activation.
J Neurosci
; 28(22): 5827-35, 2008 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-18509044
18.
Aberrant cardiolipin metabolism is associated with cognitive deficiency and hippocampal alteration in tafazzin knockdown mice.
Biochim Biophys Acta Mol Basis Dis
; 1864(10): 3353-3367, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30055293
19.
Use of a poly(ADP-ribose) polymerase inhibitor to suppress inflammation and neuronal death after cerebral ischemia-reperfusion.
Stroke
; 38(2 Suppl): 632-6, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17261705
20.
Multiple roles for poly(ADP-ribose)polymerase-1 in neurological disease.
Neurochem Int
; 50(7-8): 954-8, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17222947