Detalhe da pesquisa
1.
RNAi screen reveals synthetic lethality between cyclin G-associated kinase and FBXW7 by inducing aberrant mitoses.
Br J Cancer
; 117(7): 954-964, 2017 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28829765
2.
Cediranib in patients with relapsed platinum-sensitive ovarian cancer (ICON6): a randomised, double-blind, placebo-controlled phase 3 trial.
Lancet
; 387(10023): 1066-1074, 2016 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27025186
3.
The role of hormonal therapy in patients with relapsed high-grade ovarian carcinoma: a retrospective series of tamoxifen and letrozole.
BMC Cancer
; 17(1): 456, 2017 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28666422
4.
A study of motivations and expectations of patients seen in phase 1 oncology clinics.
Cancer
; 122(22): 3501-3508, 2016 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27716902
5.
A first in man, dose-finding study of the mTORC1/mTORC2 inhibitor OSI-027 in patients with advanced solid malignancies.
Br J Cancer
; 114(8): 889-96, 2016 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27002938
6.
Outcomes and endpoints in cancer trials: bridging the divide.
Lancet Oncol
; 16(1): e43-52, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25638556
7.
Poor performance status (PS) is an indication for an aggressive approach to neoadjuvant chemotherapy in patients with advanced epithelial ovarian cancer (EOC).
Gynecol Oncol
; 139(2): 216-20, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26318078
8.
Phase I trials in patients with relapsed, advanced upper gastrointestinal carcinomas: experience in a specialist unit.
Gastric Cancer
; 17(4): 621-629, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24445485
9.
Secondary mutations in BRCA2 associated with clinical resistance to a PARP inhibitor.
J Pathol
; 229(3): 422-9, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23165508
10.
The poly(ADP-ribose) polymerase inhibitor niraparib (MK4827) in BRCA mutation carriers and patients with sporadic cancer: a phase 1 dose-escalation trial.
Lancet Oncol
; 14(9): 882-92, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23810788
11.
Ovarian cancer: strategies for overcoming resistance to chemotherapy.
Nat Rev Cancer
; 3(7): 502-16, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12835670
12.
Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers.
N Engl J Med
; 361(2): 123-34, 2009 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19553641
13.
Advanced solid tumors treated with cediranib: comparison of dynamic contrast-enhanced MR imaging and CT as markers of vascular activity.
Radiology
; 265(2): 426-36, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22891356
14.
Phase I clinical and pharmacokinetic study of trabectedin and carboplatin in patients with advanced solid tumors.
Invest New Drugs
; 30(2): 616-28, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20927639
15.
A radiomics-based decision support tool improves lung cancer diagnosis in combination with the Herder score in large lung nodules.
EBioMedicine
; 86: 104344, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36370635
16.
PARP inhibitors: the race is on.
Br J Cancer
; 114(7): 713-5, 2016 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27022824
17.
Metastatic ovarian and primary peritoneal cancer: assessing chemotherapy response with diffusion-weighted MR imaging--value of histogram analysis of apparent diffusion coefficients.
Radiology
; 261(1): 182-92, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21828186
18.
PARP inhibitors in BRCA gene-mutated ovarian cancer and beyond.
Curr Oncol Rep
; 13(6): 442-9, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21913063
19.
Role of molecular agents and targeted therapy in clinical trials for women with ovarian cancer.
Int J Gynecol Cancer
; 21(4): 763-70, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21543938
20.
Quantitative imaging of RAD51 expression as a marker of platinum resistance in ovarian cancer.
EMBO Mol Med
; 13(5): e13366, 2021 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33709473