Detalhe da pesquisa
1.
The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer.
Cell
; 184(12): 3143-3162.e32, 2021 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34004147
2.
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.
Mol Cell
; 81(10): 2183-2200.e13, 2021 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34019788
3.
Rationally designed chimeric PI3K-BET bromodomain inhibitors elicit curative responses in MYC-driven lymphoma.
Proc Natl Acad Sci U S A
; 120(36): e2306414120, 2023 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37643213
4.
An Inflammatory Perspective on Necroptosis.
Mol Cell
; 65(6): 965-973, 2017 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28306512
5.
PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumours.
EMBO J
; 39(2): e103637, 2020 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31803974
6.
Unleashing TNF cytotoxicity to enhance cancer immunotherapy.
Trends Immunol
; 42(12): 1128-1142, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34750058
7.
HOIP limits anti-tumor immunity by protecting against combined TNF and IFN-gamma-induced apoptosis.
EMBO Rep
; 22(11): e53391, 2021 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34467615
8.
A chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence.
Genes Dev
; 29(21): 2231-43, 2015 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26494712
9.
Efficient CRISPR/Cas9 Gene Editing in Uncultured Naive Mouse T Cells for In Vivo Studies.
J Immunol
; 204(8): 2308-2315, 2020 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32152070
10.
Fas/CD95-induced chemokines can serve as "find-me" signals for apoptotic cells.
Mol Cell
; 49(6): 1034-48, 2013 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23434371
11.
Protection from EAE in DOCK8 mutant mice occurs despite increased Th17 cell frequencies in the periphery.
Eur J Immunol
; 49(5): 770-781, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30729501
12.
DOCK8 Drives Src-Dependent NK Cell Effector Function.
J Immunol
; 2017 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28794229
13.
The Role of the immunological Synapse Formed by Cytotoxic Lymphocytes in Immunodeficiency and Anti-Tumor immunity.
Crit Rev Immunol
; 35(4): 325-47, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26757394
14.
Inhibitor of apoptosis proteins (IAPs) and their antagonists regulate spontaneous and tumor necrosis factor (TNF)-induced proinflammatory cytokine and chemokine production.
J Biol Chem
; 288(7): 4878-90, 2013 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23275336
15.
Inflammatory outcomes of apoptosis, necrosis and necroptosis.
Biol Chem
; 395(10): 1163-71, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25153241
16.
Tumor immune evasion: insights from CRISPR screens and future directions.
FEBS J
; 291(7): 1386-1399, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37971319
17.
PRMT1 acts as a suppressor of MHC-I and anti-tumor immunity.
Cell Rep
; 43(3): 113831, 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38401121
18.
CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
Cell Rep
; 42(8): 113014, 2023 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37605534
19.
NKG7 Enhances CD8+ T Cell Synapse Efficiency to Limit Inflammation.
Front Immunol
; 13: 931630, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35874669
20.
Distinct modulation of IFNγ-induced transcription by BET bromodomain and catalytic P300/CBP inhibition in breast cancer.
Clin Epigenetics
; 14(1): 96, 2022 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35902886