Detalhe da pesquisa
1.
Discovery of a class of highly potent Janus Kinase 1/2 (JAK1/2) inhibitors demonstrating effective cell-based blockade of IL-13 signaling.
Bioorg Med Chem Lett
; 29(12): 1522-1531, 2019 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30981576
2.
Scaffold-Hopping and Structure-Based Discovery of Potent, Selective, And Brain Penetrant N-(1H-Pyrazol-3-yl)pyridin-2-amine Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12).
J Med Chem
; 58(20): 8182-99, 2015 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26431428
3.
Discovery of ledipasvir (GS-5885): a potent, once-daily oral NS5A inhibitor for the treatment of hepatitis C virus infection.
J Med Chem
; 57(5): 2033-46, 2014 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24320933
4.
Correction to Discovery of Ledipasvir (GS-5885): A Potent, Once-Daily Oral NS5A Inhibitor for the Treatment of Hepatitis C Virus Infection.
J Med Chem
; 59(16): 7696, 2016 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27529494