Detalhe da pesquisa
1.
In Silico Binding of 2-Aminocyclobutanones to SARS-CoV-2 Nsp13 Helicase and Demonstration of Antiviral Activity.
Int J Mol Sci
; 24(6)2023 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36982188
2.
Mycolactone: A Broad Spectrum Multitarget Antiviral Active in the Picomolar Range for COVID-19 Prevention and Cure.
Int J Mol Sci
; 24(8)2023 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37108313
3.
Carborane-Containing Hydroxamate MMP Ligands for the Treatment of Tumors Using Boron Neutron Capture Therapy (BNCT): Efficacy without Tumor Cell Entry.
Int J Mol Sci
; 24(8)2023 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37108137
4.
Structure-Based Identification of Natural-Product-Derived Compounds with Potential to Inhibit HIV-1 Entry.
Molecules
; 28(2)2023 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36677538
5.
The emerging paradigm of calcium homeostasis as a new therapeutic target for protozoan parasites.
Med Res Rev
; 42(1): 56-82, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33851452
6.
Iron dysregulation in COVID-19 and reciprocal evolution of SARS-CoV-2: Natura nihil frustra facit.
J Cell Biochem
; 123(3): 601-619, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34997606
7.
Multi-targeting approach for nsp3, nsp9, nsp12 and nsp15 proteins of SARS-CoV-2 by Diosmin as illustrated by molecular docking and molecular dynamics simulation methodologies.
Methods
; 195: 44-56, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33639316
8.
Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening pipeline and in-vitro validation assays.
Methods
; 195: 57-71, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33453392
9.
Molecular Insights into Severe Acute Respiratory Syndrome Coronavirus 2 Pathobiology: Dissecting the Interplay between Cellular Innate Immunity and Immune Evasion.
Crit Rev Immunol
; 40(6): 485-496, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33900693
10.
Antiviral evaluation of hydroxyethylamine analogs: Inhibitors of SARS-CoV-2 main protease (3CLpro), a virtual screening and simulation approach.
Bioorg Med Chem
; 47: 116393, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34509862
11.
Discovery of New Hydroxyethylamine Analogs against 3CLpro Protein Target of SARS-CoV-2: Molecular Docking, Molecular Dynamics Simulation, and Structure-Activity Relationship Studies.
J Chem Inf Model
; 60(12): 5754-5770, 2020 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32551639
12.
Genetic variation in interleukin-7 is associated with a reduced erythropoietic response in Kenyan children infected with Plasmodium falciparum.
BMC Med Genet
; 20(1): 140, 2019 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31420016
13.
Antiplasmodial activity of hydroxyethylamine analogs: Synthesis, biological activity and structure activity relationship of plasmepsin inhibitors.
Bioorg Med Chem
; 26(13): 3837-3844, 2018 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29983285
14.
Reduced Hsp70 and Glutamine in Pediatric Severe Malaria Anemia: Role of Hemozoin in Suppressing Hsp70 and NF-κB activation.
Mol Med
; 22: 570-584, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27579474
15.
Reduced Parasite Burden in Children with Falciparum Malaria and Bacteremia Coinfections: Role of Mediators of Inflammation.
Mediators Inflamm
; 2016: 4286576, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27418744
16.
Decoding Immuno-Competence: A Novel Analysis of Complete Blood Cell Count Data in COVID-19 Outcomes.
Biomedicines
; 12(4)2024 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38672225
17.
Suppressed circulating bicyclo-PGE2 levels and leukocyte COX-2 transcripts in children co-infected with P. falciparum malaria and HIV-1 or bacteremia.
Biochem Biophys Res Commun
; 436(4): 585-90, 2013 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23743193
18.
Data structuring may prevent ambiguity and improve personalized medical prognosis.
Mol Aspects Med
; 91: 101142, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36116999
19.
Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics.
Mol Aspects Med
; 91: 101151, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36371228
20.
Reduced interferon (IFN)-α conditioned by IFNA2 (-173) and IFNA8 (-884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all-cause mortality.
Hum Genet
; 131(8): 1375-91, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22570109