Detalhe da pesquisa
1.
Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPß levels in cerebrospinal fluid and 2D/3D cell culture models.
Neurobiol Dis
; 182: 106140, 2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37120095
2.
Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
Neurobiol Dis
; 85: 187-205, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26563932
3.
Organotypic Hippocampal Slice Cultures from Adult Tauopathy Mice and Theragnostic Evaluation of Nanomaterial Phospho-TAU Antibody-Conjugates.
Cells
; 12(10)2023 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37408256
4.
Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic mice.
J Cell Mol Med
; 16(6): 1206-22, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21762376
5.
Metabolite Signature of Physical Activity and the Risk of Type 2 Diabetes in 7271 Men.
Metabolites
; 12(1)2022 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35050191
6.
MECP2 Increases the Pro-Inflammatory Response of Microglial Cells and Phosphorylation at Serine 423 Regulates Neuronal Gene Expression upon Neuroinflammation.
Cells
; 10(4)2021 04 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33918872
7.
Diabetic phenotype in mouse and humans reduces the number of microglia around ß-amyloid plaques.
Mol Neurodegener
; 15(1): 66, 2020 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33168021
8.
Altered Insulin Signaling in Alzheimer's Disease Brain - Special Emphasis on PI3K-Akt Pathway.
Front Neurosci
; 13: 629, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31275108
9.
Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice.
Neurobiol Aging
; 75: 98-108, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30554086
10.
Molecular Mechanisms of Synaptotoxicity and Neuroinflammation in Alzheimer's Disease.
Front Neurosci
; 12: 963, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30618585
11.
Brain-Specific Basal and Novelty-Induced Alternations in PI3K-Akt and MAPK/ERK Signaling in a Middle-Aged AßPP/PS1 Mouse Model of Alzheimer's Disease.
J Alzheimers Dis
; 51(4): 1157-73, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26923018
12.
Cerebral dopamine neurotrophic factor improves long-term memory in APP/PS1 transgenic mice modeling Alzheimer's disease as well as in wild-type mice.
Behav Brain Res
; 291: 1-11, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25975173
13.
High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status.
J Nutr Biochem
; 25(6): 634-41, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24746833
14.
The impact of Bdnf gene deficiency to the memory impairment and brain pathology of APPswe/PS1dE9 mouse model of Alzheimer's disease.
PLoS One
; 8(7): e68722, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23844236
15.
Impaired TrkB receptor signaling contributes to memory impairment in APP/PS1 mice.
Neurobiol Aging
; 33(6): 1122.e23-39, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22209410
16.
Effects of memantine and donepezil on cortical and hippocampal acetylcholine levels and object recognition memory in rats.
Neuropharmacology
; 61(5-6): 891-9, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21704049
17.
A novel delayed non-match to sample object recognition task that allows simultaneous in vivo microdialysis.
J Neurosci Methods
; 189(2): 210-5, 2010 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20394774