Detalhe da pesquisa
1.
A phase I trial of SON-1010, a tumor-targeted, interleukin-12-linked, albumin-binding cytokine, shows favorable pharmacokinetics, pharmacodynamics, and safety in healthy volunteers.
Front Immunol
; 15: 1362775, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38487528
2.
SON-1210 - a novel bifunctional IL-12 / IL-15 fusion protein that improves cytokine half-life, targets tumors, and enhances therapeutic efficacy.
Front Immunol
; 14: 1326927, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38250068
3.
A Phase 1b Study Evaluating the Safety, Tolerability, and Immunogenicity of CMB305, a Lentiviral-Based Prime-Boost Vaccine Regimen, in Patients with Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1.
Oncoimmunology
; 9(1): 1847846, 2020 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33312760
4.
Safety and Immunogenicity of a Tetravalent Dengue DNA Vaccine Administered with a Cationic Lipid-Based Adjuvant in a Phase 1 Clinical Trial.
Am J Trop Med Hyg
; 98(3): 849-856, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29363446
5.
Dose sparing with intradermal injection of influenza vaccine.
N Engl J Med
; 351(22): 2295-301, 2004 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-15525714
6.
Survey of human-use adjuvants.
Expert Rev Vaccines
; 2(2): 167-88, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12899569
7.
Transcutaneous immunization and immunostimulant strategies: capitalizing on the immunocompetence of the skin.
Expert Rev Vaccines
; 2(2): 253-67, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12899576
8.
Transcutaneous immunization and immunostimulant strategies.
Immunol Allergy Clin North Am
; 23(4): 787-813, 2003 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-14753392
9.
A novel therapeutic cytomegalovirus DNA vaccine in allogeneic haemopoietic stem-cell transplantation: a randomised, double-blind, placebo-controlled, phase 2 trial.
Lancet Infect Dis
; 12(4): 290-9, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22237175
10.
Reanalysis of TransVax immunogenicity.
Lancet Infect Dis
; 13(1): 18, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23257230
11.
Intranasal Protollin-formulated recombinant SARS S-protein elicits respiratory and serum neutralizing antibodies and protection in mice.
Vaccine
; 25(34): 6334-40, 2007 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-17640780
12.
Improved immune responses to influenza vaccination in the elderly using an immunostimulant patch.
Vaccine
; 23(7): 946-50, 2005 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15603897
13.
Leishmania donovani-induced expression of suppressor of cytokine signaling 3 in human macrophages: a novel mechanism for intracellular parasite suppression of activation.
Infect Immun
; 71(4): 2095-101, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12654831
14.
CpG oligodeoxynucleotides protect normal and SIV-infected macaques from Leishmania infection.
J Immunol
; 170(9): 4717-23, 2003 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12707351
15.
CpG oligodeoxynucleotides as vaccine adjuvants in primates.
J Immunol
; 168(4): 1659-63, 2002 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-11823494
16.
Immunological and pathological evaluation of rhesus macaques infected with Leishmania major.
Exp Parasitol
; 103(3-4): 160-8, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-12880593
17.
Induction of protective immunity against lethal anthrax challenge with a patch.
J Infect Dis
; 190(4): 774-82, 2004 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15272406
18.
2nd meeting on novel adjuvants currently in/close to human clinical testing. World Health Organization-Organization Mondiale de la Santé Fondation Mérieux, Annecy, France, 5-7 June 2000.
Vaccine
; 20(17-18): 2155-63, 2002 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-12009267