Detalhe da pesquisa
1.
A selective inhibitor of the sperm-specific potassium channel SLO3 impairs human sperm function.
Proc Natl Acad Sci U S A
; 120(4): e2212338120, 2023 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36649421
2.
VU6036720: The First Potent and Selective In Vitro Inhibitor of Heteromeric Kir4.1/5.1 Inward Rectifier Potassium Channels.
Mol Pharmacol
; 101(5): 357-370, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35246480
3.
Structure-Activity Relationships, Pharmacokinetics, and Pharmacodynamics of the Kir6.2/SUR1-Specific Channel Opener VU0071063.
J Pharmacol Exp Ther
; 370(3): 350-359, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31201216
4.
Discovery, Characterization, and Effects on Renal Fluid and Electrolyte Excretion of the Kir4.1 Potassium Channel Pore Blocker, VU0134992.
Mol Pharmacol
; 94(2): 926-937, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29895592
5.
Pore Polarity and Charge Determine Differential Block of Kir1.1 and Kir7.1 Potassium Channels by Small-Molecule Inhibitor VU590.
Mol Pharmacol
; 92(3): 338-346, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28619748
6.
ROMK inhibitor actions in the nephron probed with diuretics.
Am J Physiol Renal Physiol
; 310(8): F732-F737, 2016 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26661652
7.
Intracellular Ca2+ silences L-type Ca2+ channels in mesenteric veins: mechanism of venous smooth muscle resistance to calcium channel blockers.
Circ Res
; 106(4): 739-47, 2010 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-20044515
8.
Further SAR on the (Phenylsulfonyl)piperazine Scaffold as Inhibitors of the Aedes aegypti Kir1 (AeKir) Channel and Larvicides.
ChemMedChem
; 16(2): 319-327, 2021 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32926544
9.
The LRRC8 volume-regulated anion channel inhibitor, DCPIB, inhibits mitochondrial respiration independently of the channel.
Physiol Rep
; 7(23): e14303, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31814333
10.
Discovery and Characterization of VU0529331, a Synthetic Small-Molecule Activator of Homomeric G Protein-Gated, Inwardly Rectifying, Potassium (GIRK) Channels.
ACS Chem Neurosci
; 10(1): 358-370, 2019 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30136838
11.
Discovery and Characterization of 2-Nitro-5-(4-(phenylsulfonyl)piperazin-1-yl)- N-(pyridin-4-ylmethyl)anilines as Novel Inhibitors of the Aedes aegypti Kir1 ( AeKir1) Channel.
ACS Infect Dis
; 5(6): 917-931, 2019 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30832472
12.
Discovery and in Vitro Optimization of 3-Sulfamoylbenzamides as ROMK Inhibitors.
ACS Med Chem Lett
; 9(2): 125-130, 2018 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29456800
13.
The shifting landscape of KATP channelopathies and the need for 'sharper' therapeutics.
Future Med Chem
; 8(7): 789-802, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27161588
14.
BK channels in rat and human pulmonary smooth muscle cells are BKα-ß1 functional complexes lacking the oxygen-sensitive stress axis regulated exon insert.
Pulm Circ
; 6(4): 563-575, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28090300
15.
ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium Channels.
ACS Chem Neurosci
; 7(7): 1013-23, 2016 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27184474
16.
Mrg19 depletion increases S. cerevisiae lifespan by augmenting ROS defence.
FEBS Lett
; 579(30): 6809-13, 2005 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-16336970
17.
Tocotrienol-Rich Fraction from Rice Bran Demonstrates Potent Radiation Protection Activity.
Evid Based Complement Alternat Med
; 2015: 148791, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26425129
18.
Cardiac and renal inward rectifier potassium channel pharmacology: emerging tools for integrative physiology and therapeutics.
Curr Opin Pharmacol
; 15: 7-15, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24721648
19.
The ß3 subunit contributes to vascular calcium channel upregulation and hypertension in angiotensin II-infused C57BL/6 mice.
Hypertension
; 61(1): 137-42, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23129698
20.
Plight of the pore polar bar(rier).
Channels (Austin)
; 11(6): 502-503, 2017 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28806132