Detalhe da pesquisa
1.
Emicizumab prophylaxis in infants with hemophilia A (HAVEN 7): primary analysis of a phase 3b open-label trial.
Blood
; 143(14): 1355-1364, 2024 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38127586
2.
Effect of emicizumab prophylaxis on bone and joint health markers in people with haemophilia A without factor VIII inhibitors in the HAVEN 3 study.
Haemophilia
; 28(6): 1033-1043, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-35905294
3.
Low immunogenicity of emicizumab in persons with haemophilia A.
Haemophilia
; 27(6): 984-992, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34480814
4.
Crovalimab for treatment of patients with paroxysmal nocturnal haemoglobinuria and complement C5 polymorphism: Subanalysis of the phase 1/2 COMPOSER study.
Br J Haematol
; 198(3): e46-e50, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35608260
5.
Functional analysis and transcriptional output of the Göttingen minipig genome.
BMC Genomics
; 16: 932, 2015 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26573612
6.
Circulating tumor DNA and circulating tumor cells in metastatic triple negative breast cancer patients.
Int J Cancer
; 136(9): 2158-65, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25307450
7.
Case report of a fatal rectal haemorrhage in a person with severe haemophilia A receiving emicizumab and high-dose bypassing agents in the HAVEN 1 study.
Haemophilia
; 26(6): e340-e342, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32700348
8.
The immunogenicity of antibody aggregates in a novel transgenic mouse model.
Pharm Res
; 32(7): 2344-59, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25630815
9.
Pharmacokinetics and coagulation biomarkers in children and adults with hemophilia A receiving emicizumab prophylaxis every 1, 2, or 4 weeks.
Res Pract Thromb Haemost
; 8(1): 102306, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38282901
10.
Clinical pharmacology of emicizumab for the treatment of hemophilia A.
Expert Rev Clin Pharmacol
; 16(9): 775-790, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37529848
11.
DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia.
Blood
; 115(6): 1214-25, 2010 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-19965625
12.
Safety and efficacy of long-term emicizumab prophylaxis in hemophilia A with factor VIII inhibitors: A phase 3b, multicenter, single-arm study (STASEY).
Res Pract Thromb Haemost
; 6(8): e12837, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36397934
13.
Evaluation of the Pharmacokinetics, Pharmacodynamics, and Safety of a Single Dose of Emicizumab in Healthy Chinese Subjects.
Clin Pharmacol Drug Dev
; 10(1): 30-38, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32433829
14.
DAP12/TREM2 deficiency results in impaired osteoclast differentiation and osteoporotic features.
J Exp Med
; 198(4): 669-75, 2003 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-12925681
15.
Stromal organization as predictive biomarker for the treatment of colon cancer with adjuvant bevacizumab; a post-hoc analysis of the AVANT trial.
Cell Oncol (Dordr)
; 42(5): 717-725, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31102145
16.
The Genome Sequence of the Eastern Woodchuck (Marmota monax) - A Preclinical Animal Model for Chronic Hepatitis B.
G3 (Bethesda)
; 9(12): 3943-3952, 2019 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31645421
17.
Efficacy, safety, and pharmacokinetics of emicizumab prophylaxis given every 4 weeks in people with haemophilia A (HAVEN 4): a multicentre, open-label, non-randomised phase 3 study.
Lancet Haematol
; 6(6): e295-e305, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-31003963
18.
Transcript profiles of dendritic cells of PLOSL patients link demyelinating CNS disorders with abnormalities in pathways of actin bundling and immune response.
J Mol Med (Berl)
; 85(9): 971-83, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17530208
19.
A transcriptionally and functionally distinct PD-1+ CD8+ T cell pool with predictive potential in non-small-cell lung cancer treated with PD-1 blockade.
Nat Med
; 24(7): 994-1004, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29892065
20.
Dual angiopoietin-2 and VEGFA inhibition elicits antitumor immunity that is enhanced by PD-1 checkpoint blockade.
Sci Transl Med
; 9(385)2017 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28404865