Detalhe da pesquisa
1.
Fragment based discovery of a novel and selective PI3 kinase inhibitor.
Bioorg Med Chem Lett
; 21(21): 6586-90, 2011 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21925880
2.
Discovery of Clinical Candidate 1-{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design.
J Med Chem
; 60(13): 5521-5542, 2017 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28498658
3.
Effect of JAK Inhibitors on Release of CXCL9, CXCL10 and CXCL11 from Human Airway Epithelial Cells.
PLoS One
; 10(6): e0128757, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26090665
4.
Design and synthesis of inhaled p38 inhibitors for the treatment of chronic obstructive pulmonary disease.
J Med Chem
; 54(22): 7797-814, 2011 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21888439